Objective:to evaluate the usefulness of capnography for the detection of metabolic changes
in spontaneous breathing patients, in the emergency and intensive care settings.
Methods:in-depth and structured bibliographical search in the databases EBSCOhost, Virtual
Health Library, PubMed, Cochrane Library, among others, identifying studies that
assessed the relationship between capnography values and the variables involved in
blood acid-base balance. Results:19 studies were found, two were reviews and 17 were observational studies. In nine
studies, capnography values were correlated with carbon dioxide (CO2),
eight with bicarbonate (HCO3), three with lactate, and four with blood
pH. Conclusions:most studies have found a good correlation between capnography values and blood
biomarkers, suggesting the usefulness of this parameter to detect patients at risk
of severe metabolic change, in a fast, economical and accurate way.