Predictive Value of acoustic cardiography for post-PCI early ventricular remodeling in acute myocardial infarction patients

Abstract

To investigate the clinical value of SDI,EMATc,BNP in the predictive of post-PCI early ventricular remodeling (EVR) in patients with acute myocardial infarction (AMI). 161 patients with asymptomatic acute anterior wall myocardial infarction after PCI were involved; BNP and acoustic cardiography were performed in pre-operation, Color Doppler echocardiography was performed after 72 hours. The patients were divided into two groups, which were the EVRgroup (EF% < 50%, EVR) and the normal left ventricular systolic function group (EF% ≥ 50%, Non- EVR). EMATc、SDI、BNP were independent risk factors for post-PCI EVRin patients with AMI [SDI (OR 15.924, 95% CI 3.649-69.491, p≤0.001) ,EMATc (OR 2.319, 95% CI 1.447-3.719, p＜0.001 ) and BNP (OR 1.075, 95% CI 1.018-1.134,p=0.009)]. The area under the ROC curve (AUC) for EMATc was 0.89, with an optimal cutoff point of 12.2, EMATc produced a sensitivity of 80% and a specificity of 83%; whereas, with an optimal cutoff point of 100pg/ml, BNP produced a sensitivity of 46% and a specificity of 83%. EMATc、BNP、SDI have good predictive value for the occurrence of EVR in patients with asymptomatic acute anterior wall myocardial infarction after PCI.