Predictive modeling for cell culture in commercial manufacturing of biotherapeutics
Shyam Panjwani,
Alice Almazan,
Rubin Hille
et al.
Abstract:The biopharmaceutical industry continually seeks advancements in the commercial manufacturing of therapeutic proteins, where mammalian cell culture plays a pivotal role. The current work presents a novel data‐driven predictive modeling application designed to enhance the efficiency and predictability of cell culture processes in biotherapeutic production. The capability of the cloud‐based digital data science application, developed using open‐source tools, is demonstrated with respect to predicting bioreactor … Show more
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