Predictive markers of acute focal bacterial nephritis. A multicentre case-control study

Is shorter antibiotic treatment duration increasing the risk of relapse in paediatric acute focal bacterial nephritis?

“…It is unclear whether underlying uropathology might be a risk factor for AFBN and especially for relapse in AFBN. While there is some evidence for higher rates of vesico-urethral reflux in children with AFBN compared with acute pyelonephritis,6 other studies in the literature do not confirm this association1 5 13–19 (see online supplemental table 1).…”

“…Furthermore, data suggest that patients with AFBN have higher inflammatory parameters as well as higher temperatures at presentation 5. In a retrospective, multicentre study from Spain, procalcitonin values ≥2 ng/mL had an OR of 4.9 (95% CI 1.77 to 13.85) for AFBN compared to upper UTI 6…”