2014
DOI: 10.1007/s11695-014-1391-y
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Predictive Factors of Type 2 Diabetes Mellitus Remission Following Bariatric Surgery: a Meta-analysis

Abstract: BackgroundAlthough a few studies have been reported on predictive factors of postoperative diabetes remission, the conclusions remain inconsistent. This meta-analysis aimed to assess the preoperative clinical factors for type 2 diabetes mellitus (T2DM) remission after bariatric surgery.MethodsThe Cochrane Library, PubMed, MEDLINE, Embase, and CINAHL databases were searched. All human studies published in English between 1 January 1992 and 1 September 2013 reporting on the parameters of interest were included.R… Show more

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Cited by 111 publications
(93 citation statements)
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“…Advanced age, diabetes duration, insulin use, and HbA 1c levels are inversely related to postoperative diabetes remission (29). Duration of diabetes and insulin or oral management as proxy for disease severity were not used for inclusion/exclusion criteria in our study.…”
Section: Discussionmentioning
confidence: 99%
“…Advanced age, diabetes duration, insulin use, and HbA 1c levels are inversely related to postoperative diabetes remission (29). Duration of diabetes and insulin or oral management as proxy for disease severity were not used for inclusion/exclusion criteria in our study.…”
Section: Discussionmentioning
confidence: 99%
“…A recent metaanalysis of 15 studies (n = 1753) analyzed several characteristics of patient who remitted following bariatric surgery. Older age, long duration of diabetes, current insulin use and poor glycemic control were associated with negative predictors of diabetes remission, while gender and preoperative BMI had no significant association for both Asian and non-Asian obese T2DM patients [125]. However, Asian T2DM patients showed better remission rate of diabetes and correlated well with the lower severity of T2DM.…”
Section: Predictive Factors For T2dm Remission After Bariatric Surgerymentioning
confidence: 87%
“…Thus, age, duration of diabetes and appropriate glycemic control could be one of the selective criteria for predicting diabetes remission. Furthermore, disease severity appeared to be an important predictive factor, particularly for Asian patients as T2DM in Asian patients is associated with severe impairment of b-cell function and patients dependent on insulin therapy might have worse b-cell function [125]. Kim et al suggested higher BMI could also hold a predictive value for the success of metabolic surgery in T2DM [126].…”
Section: Predictive Factors For T2dm Remission After Bariatric Surgerymentioning
confidence: 99%
“…(17) Edelman et al found no relationship between baseline BMI and improvement of glycated hemoglobin (HbA1c) one year after gastric banding in 187 patients with baseline BMI≥35kg/m2. (18) Schauer et al reported the same for lower BMI, comparing T2DM medication and HbA1c one year after sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass (LRYGB) between 68 patients with baseline BMI≥35kg/m 2 and 32 with BMI<35kg/m 2 .…”
Section: Introductionmentioning
confidence: 99%