Predictive factors of fibrosis progression in patients with mild hepatitis C

Worsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies

“…In the present study, fibrosis progression was observed in approximately 30% of our patients over a mean period of four years, a rate consistent with previous reports. 32 33 The availibity of paired liver biopsies gave us the opportunity to assess steatosis evolution over time, a parameter not studied to date.…”