Predictive factors for tooth loss during supportive periodontal therapy in patients with severe periodontitis: a Japanese multicenter study

Abstract

BackgroundSupportive periodontal therapy (SPT) must take individual patient risk factors into account. We conducted a multicenter joint retrospective cohort study to investigate the value of modified periodontal risk assessment (MPRA) and therapy-resistant periodontitis (TRP) assessment as predictive factors for tooth loss due to periodontal disease in patients with severe periodontitis during SPT.MethodsThe subjects were 82 patients from 11 dental institutions who were diagnosed with severe periodontitis and continued SPT for at least 1 year (mean follow-up = 4.9 years) between 1981 and 2008. The outcome was tooth loss due to periodontal disease during SPT. The Cox proportional hazards model was used to analyze sex, age, diabetes status, smoking history, number of periodontal pockets measuring ≥6 mm, rate of bleeding on probing, bone loss/age ratio, number of teeth lost, MPRA, and TRP assessment as explanatory variables.ResultsUnivariate analysis showed that loss of ≥8 teeth by the start of SPT [hazard ratio (HR) 2.86], MPRA score indicating moderate risk (HR 8.73) or high risk (HR 11.04), and TRP assessment as poor responsiveness to treatment (HR 2.79) were significantly associated with tooth loss (p < 0.05). In a model in which the explanatory variables of an association that was statistically significant were added simultaneously, the HR for poor responsiveness to treatment and ≥8 teeth lost was significant at 20.17 compared with patients whose TRP assessment indicated that they responded favorably to treatment and who had lost <8 teeth by the start of SPT.ConclusionMPRA and TRP assessment may be useful predictive factors for tooth loss due to periodontal disease during SPT in Japanese patients with severe periodontitis. Additionally, considering the number of teeth lost by the start of SPT in TRP assessment may improve its predictive accuracy.

Dose‐dependent effect of smoking and smoking cessation on periodontitis‐related tooth loss during 10 ‐ 47 years periodontal maintenance—A retrospective study in compliant cohort

“…Retrospective studies were performed based on patient charts at dental schools in Canada where a Dalhousie study reported a mean TLP of 0.06/patient/year (Matthews, Smith, & Hanscom, 2001) and one in Manitoba reported a mean TLP of 0.016/patient/year (Fisher et al, 2008). A Japanese multisite university-based study calculated a mean of 0.040 TLP/patient/year among PMT compliant patients (Hirata, Fuchida, Yamamoto, Kudo, & Minabe, 2019). These three studies found smoking to not be associated with TLP.…”

A 5-year prospective validation of the Miller–McEntire Periodontal Prognostic Index

“…In addition, other prognostic factors such as bone loss/age ratio, number of teeth lost, and comparison with other prognostic tools such as periodontal risk assessment and therapy-resistant periodontitis assessment warrant investigation in future. [ 21 ]…”

The Impact of Expanded National Health Insurance Coverage of Dentures and Dental Implants on Dental Care Utilization among Older Adults in South Korea: A Study Based on the Korean Health Panel Survey

“…Multiple tooth loss in older people is the cumulative result of dental caries and periodontal diseases that have occurred throughout their lives [ 8 , 9 ]. To restore oral functions hindered by multiple tooth loss, costly dental prosthetic services, such as dentures and dental implants, are needed.…”