Predictive Factors for
Successful Surgical Outcome of
Benign Prostatic Hypertrophy

Kuo, Hann‐Chorng; Chang, Shih-Chung; Hsu, Tsi

doi:10.1159/000474255

Cited by 22 publications

(13 citation statements)

References 9 publications

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“…The impact of traditionally used subjective and objective parameters on treatment outcome has been studied [10][11][12] , but the results are not reliable. In this study, all parameters after TURP changed significantly, from 55.1 to 116%, and that determined the overall effectiveness of the treatment.…”

Section: Discussionmentioning

confidence: 99%

Transition Zone Index and Bothersomeness of Voiding Symptoms as Predictors of Early Unfavorable Outcomes after Transurethral Resection of Prostate

Milonas¹,

Šaferis²,

Jievaltas³

2008

Urol Int

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Introduction: The objective of this study was to establish the influence of preoperative parameters on unfavorable outcomes after transurethral resection of the prostate. Patients and Methods: In a prospective study, 90 patients underwent transurethral resection of the prostate. The standardized protocol was used to investigate parameters, preoperatively and after 6 months. The baseline values were analyzed with respect to the probability of predicting the effectiveness of the outcome. Results: All preoperative parameters changed significantly, from 55.1 to 116% (p < 0.001). Treatment was effective for 85.6% of the patients, and the outcomes were unfavorable for 14.4%. The monovariate analysis detected the transition zone index (cut-off 0.48, p = 0.002, OR 7.48) as independent predictor of ineffective outcome. Logistic regression analysis found two the most important parameters – transition zone index (OR 30.26, p = 0.002) and bothersomeness of voiding symptoms (OR 20.7, p = 0.008) for unfavorable outcomes. Conclusions: The parameters that are traditionally used cannot predict unfavorable outcomes. The transition zone index and bothersomeness of voiding symptoms are most important parameters for predicting an unfavorable outcome after TURP.

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Section: Discussionmentioning

confidence: 99%

Transition Zone Index and Bothersomeness of Voiding Symptoms as Predictors of Early Unfavorable Outcomes after Transurethral Resection of Prostate

Milonas¹,

Šaferis²,

Jievaltas³

2008

Urol Int

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“…0.52 [11]. The configuration of the prostatic transitional zone was also recorded as: (1) no evidence of transitional zone hyperplasia; (2) mild transitional zone hyperplasia; (3) marked transitional hyperplasia; (4) diffuse inflammatory change without remarkable transitional zone hyperplasia, and (5) prominent median lobe hyperplasia alone [12]. Uroflowmetry was determined using a Dantec Urodyne 1000 machine at a bladder capacity that made the patients feel the urge to urinate.…”

Section: Methodsmentioning

confidence: 99%

“…The maximum flow rate (Qmax, in ml/s), voided volume, and the corrected maximum flow rate (CQmax = Qmax/voided volume 0.5 ) were recorded [13]. The flow patterns were also recorded as normal, compressive obstructive, and constrictive obstructive patterns [12]. Residual urine determination was performed by abdominal sonography (Bruel & Kjaer model 1851) after uroflowmetry.…”

Section: Methodsmentioning

confidence: 99%

Comparative Study of Therapeutic Effect of Dibenyline, Finasteride, and Combination Drugs for Symptomatic Benign Prostatic Hyperplasia

Kuo¹

1998

Urol Int

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Objectives: A prospective study was conducted in a community hospital in order to evaluate the therapeutic effect of dibenyline, finasteride, and a combination of the two drugs for symptomatic benign prostatic hyperplasia (BPH). Methods: 190 men suffering from severe prostatism entered this study. They were assessed by IPSS symptom score, digital rectal examination, transrectal sonography of the prostate, uroflowmetry and residual urine. The patients were randomly selected for medical treatment with dibenyline 10 mg b.i.d. (n = 71), finasteride 5 mg q.d. (n = 54), and a combination (n = 65). Clinical assessments were carried out before treatment and 3 and 6 months after starting treatment. Patients who could not complete the treatment and those with prostatic cancer were excluded from the final statistics. The quality of life after 6 months of treatment and side effects were also assessed. Results: A total of 172 patients completed the treatment course and 153 patients completed the periodic clinical assessments. Improvement in IPSS was noted in all 3 groups of patients both at 3 and 6 months. The prostatic volume was found to decrease in the finasteride group and the combination group at 6 months by 24.3 and 10.5%, respectively. Maximal flow rate (Qmax) was significantly improved in the dibenyline and combination groups but not in the finasteride group at 3 months. At 6 months a significant increase in Qmax was noted in all groups with a mean increase of 1.4–1.8 ml/s. The quality of life after treatment was satisfactory in 71.9% of the dibenyline group, 70.4% of the finasteride group and 83.1% of the combination group. Side effects were higher in the dibenyline than the finasteride or combination group. The dropout rate was higher in the dibenyline group (15.5%) than in the finasteride (7.5%) and combination (4.6%) groups. After 6 months of treatment, some of the patients discontinued medication and symptom relapse was noted in 92.6% of the dibenyline group, 57.6% of the finasteride group, and 71% of the combination group. Conclusions: Medical treatment is effective in treating symptomatic BPH. Combination dibenyline and finasteride provides a weak synergistic clinical effect without additive side effects.

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“…The prostatic size was measured using the equation: height x width x length of the outer gland x 0.52 [17], Men with any evidence of small or large prostatic hyperplasia were withdrawn from the study. Recognition of prostatic hyperplasia was based upon the observation of prostatic configuration and presence of a prominent inner gland [18]. Thus, only asymptomatic men with out prostatic hyperplasia were included in the final statistics.…”

Section: Methodsmentioning

confidence: 99%

The Uroflowmetry in Normal Men and after Prostatectomy

Kuo¹

1997

Eur Urol

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Predictive Factors for Successful Surgical Outcome of Benign Prostatic Hypertrophy

Cited by 22 publications

References 9 publications

Transition Zone Index and Bothersomeness of Voiding Symptoms as Predictors of Early Unfavorable Outcomes after Transurethral Resection of Prostate

Transition Zone Index and Bothersomeness of Voiding Symptoms as Predictors of Early Unfavorable Outcomes after Transurethral Resection of Prostate

Comparative Study of Therapeutic Effect of Dibenyline, Finasteride, and Combination Drugs for Symptomatic Benign Prostatic Hyperplasia

The Uroflowmetry in Normal Men and after Prostatectomy

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