Predictive Factors for Successful High Myopia Treatment Using High-Frequency Laser-In-Situ Keratomileusis

Abstract

Aim:To evaluate the predictive factors of LASIK procedure for high myopia with or without astigmatism using a combination of high-frequency femtosecond-assisted LASIK followed by an excimer laser.Methods:This study was a retrospective interventional case series study to evaluate myopic eyes undergoing high platform LASIK with FEMTO LDV Z2 intervention, followed by WaveLight®EX500 excimer laser machine. Subjects were divided into 2 groups: high myopia (SE of -6.01 to -9.00 D) and very high myopia (SE of -9.01 D or higher). Myopic eyes (Spherical Equivalent/SE) less than –13 D were included in this study. Visual Acuity (VA) was evaluated 1 day and 60 days after the procedure. Predictive factors, such as age, degree of sphere, degree of astigmatism, keratometric reading and axial length were analyzed to detect any influences affecting the final VA results.Results:A total of 316 myopia eyes underwent intervention, mean age: 25.3±3.8 years. Target treatment was achieved in 96.1% of patients with high myopia and 69.9% of patients with very high myopia. High degree of sphere and astigmatism constitutes an important factor influencing final VA.Conclusion:Modern machines provide a more promising efficacy and success of LASIK procedure in high myopia: important predictive factors were a high degree of sphere and astigmatism for achieving the optimal final outcome.

Predictability of the Refractive Effect after Laser Correction. Determining Factors. Review

“…Точный механизм, обусловливающий регресс рефракционного результата после FemtoLASIK, также активно изучается. Многие исследователи, в том числе W. Artini, S. Riyanto, A.S. Chayet, Chen, предполагают, что регресс рефракционного результата связан с такими факторами, как возраст, степень миопии, толщина FLAP (клапана), показатели кератометрии и предоперационный астигматизм, толщина эпителия роговицы [7,29,39,41].…”

“…[41], которые отметили прогрессивное увеличение центральной толщины роговицы на глазах с рефракционным регрессом в сроки наблюдения 3 месяца. Согласно их предположению увеличение толщины роговицы играет огромную роль в развитии миопического сдвига, и в скором времени они предложили в качестве ключевого механизма, компенсирующего изменения изначального профиля роговицы, считать ремоделирование эпителия [7,39]. Согласно теории Dierick и соавт.…”

The 25th Anniversary of Laser Vision Correction in the United States

“…25,26 Newer developments have led to wavefront-guided and wavefront-optimized treatments that have minimized induction of higher order aberrations after refractive surgery. [27][28][29][30][31] Topography guided ablations have provided the ability to treat irregular corneal topographic patterns and some studies have shown they may achieve even better uncorrected vision with normal topographic patterns. 28 Other procedures began developing such as small incision lenticule extraction (SMILE) and phakic intraocular procedures with lens implanted either in front or behind the iris (IOLS).…”