Predictive factors for detecting malignancy in central and lateral cervical lymph nodes in papillary carcinoma of the thyroid

Abstract

The involvement of the central neck should be a major indication of lymph node biopsy and pathological diagnosis regardless of the imaging findings. In the lateral compartment, hypoechogenicity with loss of hilum, microcalcifications, cystic parts and an index value ≥ 0.51 are indications of a lymph node biopsy to rule out malignancy.

A real‐time prediction model for post‐irradiation malignant cervical lymph nodes

“…It is reported that the nondiagnostic rate of FNA is higher at level VI than at lateral compartment in patients who had received surgery of the central neck. 28,29 In this scenario, it is suggested to repeat biopsy of the central nodes until an unequivocal diagnosis is made. 28,29 Certain limitations of this study should be noted.…”

“…28,29 In this scenario, it is suggested to repeat biopsy of the central nodes until an unequivocal diagnosis is made. 28,29 Certain limitations of this study should be noted. First, it may be subjected to selection bias because only those patients who had received US and USgFNA were included.…”

“…Furthermore, other clinical examinations should also be referred before deciding not to perform an aspiration to the node. It is reported that the nondiagnostic rate of FNA is higher at level VI than at lateral compartment in patients who had received surgery of the central neck . In this scenario, it is suggested to repeat biopsy of the central nodes until an unequivocal diagnosis is made …”

US‐guided core‐needle biopsy versus US‐guided fine‐needle aspiration of suspicious cervical lymph nodes for staging workup of non‐head and neck malignancies: A propensity score matching study

“…US‐guided fine‐needle aspiration (USFNA) is an easy, safe, and cost‐effective technique for diagnosing malignant lymph nodes in the head and neck with a variable range of diagnostic accuracy from 79% to 94.5% . Studies comparing USFNA and US‐guided core‐needle biopsy (USCNB) have reported that the diagnostic performance of USCNB is superior or comparable to that of USFNA in different regions in the body .…”

“…5,6 US-guided fine-needle aspiration (USFNA) is an easy, safe, and cost-effective technique for diagnosing malignant lymph nodes in the head and neck with a variable range of diagnostic accuracy from 79% to 94.5%. [7][8][9][10][11][12] Studies comparing USFNA and US-guided coreneedle biopsy (USCNB) have reported that the diagnostic performance of USCNB is superior or comparable to that of USFNA in different regions in the body. [13][14][15][16][17][18][19][20][21] In the head and neck region, USCNB has proven to have advantages over USFNA for the diagnosis of lymphoma involving the cervical lymph nodes or the thyroid gland, detection of malignant salivary gland neoplasms, as well as for the final diagnosis of initially non-diagnostic thyroid nodules.…”