Predictive correlations for the toxicity of alkyl- and halogen- substituted phenols

Applicability of CATALYST in Ecotoxicology, a New Promising Tool for 3D-QSAR: Study of Chlorophenols

“…In the "rst stage, an exhaustive search of the literature was carried out. Data were gathered on bacteria (Beltrame et al, 1984(Beltrame et al, , 1988Blum and Speece, 1991;Devillers et al, 1986;Liu et al, 1982;Seydel, 1988, 1990;Ribo and Kaiser, 1983;Tang et al, 1992), fungi yeasts (Cohen et al, 1988;Nendza and Seydel, 1988;RuK ckdeschel and Renner, 1986), protozoae (Devillers et al, 1987;Jaworska and Schultz, 1991;Pirselova et al, 1996;Schultz and Riggin, 1985;Schultz et al, 1986Schultz et al, , 1989Schultz, 1987;Schultz and Cajina-Quezada, 1987), algae (Nendza and Seydel, 1988), invertebrates copepod (Devillers and Chambon, 1986a, b;Kopperman, et al, 1974;Nendza and Seydel, 1988;Ribo and Kaiser, 1983;Smith et al, 1994), "sh (for general data: Benoit-Guyod and Clavel, 1984;Blum and Speece, 1991;Devillers and Chambon, 1986b;Devillers et al, 1989;Gao et al, 1992;Phipps et al, 1981;Ribo and Kaiser, 1983;Schultz et al, 1986;Smith et al, 1994 and for data measured at di!erent pH media values: KoK nemann and Musch, 1981;Viluksela, 1981, 1982), uncoupling and inhibitory properties (Ravanel et al, 1985(Ravanel...…”