2016
DOI: 10.1007/s11306-016-1018-5
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Predictive biomarkers and metabolic hallmark of postoperative hypoxaemia

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Cited by 12 publications
(27 citation statements)
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References 56 publications
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“…This is in accordance with our previous findings regarding predictive biomarkers of lung injury based on samples collected at 16 h post-CPB30, indicating that the development of hypoxaemia can be predicted earlier than previously thought.…”
Section: Discussionsupporting
confidence: 93%
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“…This is in accordance with our previous findings regarding predictive biomarkers of lung injury based on samples collected at 16 h post-CPB30, indicating that the development of hypoxaemia can be predicted earlier than previously thought.…”
Section: Discussionsupporting
confidence: 93%
“…In addition, increased circulating free fatty acids two hours after CABG have been identified as being early signs of postoperative hypoxaemia6. In line with these findings, we have recently shown that it was possible to predict PaO 2 measured on the third day postoperatively from a blood sample collected on the first postoperative morning30. A pattern of disturbed metabolism was observed, of which changes in ketones, amino acids, and lipid metabolism were dominant.…”
supporting
confidence: 67%
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“…For all tests, class separations were considered significant at p 0.05. In addition, partial least squares-regression models were constructed to identify possible covariance between the mucus metabolites (X-variables) and the various biological endpoints measured by Cavallin et al [9], each used individually as a single Y-variable per model [16,17]. Targeted data from Cavallin et al [9] were log-transformed, meancentered, and scaled to unit variance.…”
Section: Statistical Analysesmentioning
confidence: 99%