Predictive accuracy of the first trimester Doppler scan: a meta-study

Matevosyan, Naira R.

doi:10.1007/s10354-015-0358-5

Cited by 5 publications

(10 citation statements)

References 75 publications

(89 reference statements)

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“…Further, a recent meta-analysis showed that the most effective predictive parameter for PE is the placental side UtA RI. [14] However, consistent with the findings of other studies, [20–22] our results indicated that placental-side PI can significantly improve the prediction of PE. Nevertheless, our study is the largest study conducted thus far in a homogenous Chinese population for the assessment of the value of placenta-side UtA PI in predicting early-onset PE.…”

Section: Discussionsupporting

confidence: 92%

“…Traditionally, the PI is measured on the left- and right-side UtAs, and the mean of the 2 measurements is used in the prediction of PE. [14] A previous study has shown that the lowest UtA PI value was the most effective in predicting PE and that it has the best performance. [11] However, in that study, [11] the authors did not specify the placental laterality, assuming that the vessel with the lower PI is likely to be the placental one.…”

Section: Discussionmentioning

confidence: 99%

“…However, another recent meta-analysis, which comprised 76 studies and included a sample of 298,329 prenatal Doppler screenings performed in nulliparous women during the first trimester and early period of the second trimester in singleton pregnancies, concluded that the first-trimester UtA Doppler study has limited value in predicting adverse perinatal outcomes. [14]…”

Section: Discussionmentioning

confidence: 99%

“…Various UtA Doppler parameters have been evaluated for their effectiveness in predicting PE. [11–14] Although, traditionally, the pulsatility index (PI) is measured in both the UtAs and the mean of the 2 measurements is used to predict PE, the lowest UtA PI has been shown to be the best predictive value performance. [11] Nevertheless, studies on the value of UtA Doppler velocimetry in the prediction of PE have shown variable levels of sensitivity.…”

Section: Introductionmentioning

confidence: 99%

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First trimester Doppler velocimetry of the uterine artery ipsilateral to the placenta improves ability to predict early-onset preeclampsia

et al. 2019

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This study sought to investigate the effects of placental laterality on the measurements of uterine artery (UtA) Doppler velocimetry and their application in predicting early-onset preeclampsia (PE). We conducted a prospective cohort study on all women with singleton, uncomplicated pregnancies scheduled for first-trimester nuchal translucency at our institution. Pulsatility index (PI) for both UtAs was measured by Doppler velocimetry, and placental laterality was determined. Additionally, pregnancy outcome data were abstracted from the medical records. Receiver operating characteristic curves (ROCs) were plotted. Of the 304 patients enrolled, 247 met the inclusion criteria. Among these patients, 240 had uncomplicated delivery, while 7 had early delivery at <34 weeks due to PE. For the uncomplicated pregnancies, PI measurements of the UtA ipsilateral to the placenta were similar (left versus right UtA: 1.06 ± 0.38 vs. 1.04 ± 0.40; P = .745). However, PI measurements of the UtA contralateral to the placenta differed significantly (left versus right UtA: 1.45 ± 0.51 vs. 1.3 ± 0.47; P = .027). In predicting early-onset PE, the ideal cut-off value for the placental side PI was 1.91, with sensitivity 100% and specificity 96.3%. For nonplacental side PI, the ideal cut-off value for PI was 1.975, with sensitivity 57.1% and specificity 79.2%. Using the mean of the left and right UtA PI, the ideal cut-off value was 1.63, with sensitivity 100% and specificity 74.2%. ROC analysis confirmed that PI measurements of the UtA on the placental side were significantly lower than those on the contralateral side, PI measurements of the UtA ipsilateral to the placenta were similar.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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First trimester Doppler velocimetry of the uterine artery ipsilateral to the placenta improves ability to predict early-onset preeclampsia

et al. 2019

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“…Several UtA Doppler characteristics have been tested for their ability to predict PE [11,12]. Although the pulsatility index (PI) has typically been assessed in both UtAs and the mean of the two readings is used to predict PE, the lowest UtA PI has been proven to have the greatest predictive value performance [13]. Nonetheless, research on the use of UtA Doppler velocimetry in the prediction of PE has shown varying degrees of sensitivity.…”

Section: Introductionmentioning

confidence: 99%

Early Uterine and Umbilical Artery Doppler Indices as Predictor for Preeclampsia and Intrauterine Growth Restriction

Khalil

Elnamory

Omar

et al. 2021

JAMMR

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Background: Preeclampsia (PE) is a disorder that causes hypertension and proteinuria after week 20 of pregnancy. Several Uterine Artery (UtAs) Doppler characteristics have been investigated for their ability to predict PE. The purpose of this research is to look into the uterine and umbilical arterial Doppler indices in the early second trimester for the prediction of late preeclampsia or intrauterine growth restriction. Methods: This is a prospective cohort clinical study and was done at Obstetrics and Gynecology department, faculty of medicine Tanta university hospital from January 2020 till April 2021. 150 pregnant women aged from 18 to 30 years old with gestational age from 13 to 16 weeks of pregnancy. Study was done by the same observer by machine MINDRAY DC60 Measurement of fetal biometry (BPD, FL, AC, HC) Gestational age was confirmed with Detection of congenital malformation. Results: There is a significant difference between the groups regarding uterine and umbilical artery doppler Indices. Uterine RI only yielded significance for predicting IUGR with sensitivity of 62% and specificity of 88%, with Positive predictive value (PPV) 37% and Negative predictive value (NPV) 92%. Umbilical resistance index achieved sensitivity of 56% and specificity of 82%, with PPV 31% and NPV 30% with on statistical significance. Conclusions: Combination of uterine and umbilical artery Doppler study in early pregnancy is one of the best indicator for prediction of preeclampsia and IUGR. Therefore, Doppler study may be used for the prediction of preeclampsia and IUGR to reduce the maternal and perinatal morbidity and mortality.

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Ultrasonography: The Global Imaging Solution

Elias

Nogueira-Barbosa

2016

Curr Radiol Rep

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Predictive accuracy of the first trimester Doppler scan: a meta-study

Abstract: Predictive sensitivity of the UAD increases after 16 weeks + 3 days (115 days) of gestation. The best predictive parameter of preeclampsia and FGR is the placental side uterine artery resistance index which confers to the highest means when the placenta is on the midline (OR 0.9).

Cited by 5 publications

References 75 publications

First trimester Doppler velocimetry of the uterine artery ipsilateral to the placenta improves ability to predict early-onset preeclampsia

First trimester Doppler velocimetry of the uterine artery ipsilateral to the placenta improves ability to predict early-onset preeclampsia

Early Uterine and Umbilical Artery Doppler Indices as Predictor for Preeclampsia and Intrauterine Growth Restriction

Ultrasonography: The Global Imaging Solution

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