Prediction of traumatic wound infection with a neural network-derived decision model

Lammers, Richard L.; Hudson, Donna L.; Seaman, Matthew

doi:10.1053/ajem.2003.50026

Cited by 65 publications

(59 citation statements)

References 39 publications

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“…Few studies on the infection rate of simple hand laceration have been mostly focused on the benefits of prophylactic antibiotics. [3][4][5][6] The infection rate ranges from 5% to 32%, [3][4][5][6][7] which originates from the differences in study designs, types of antibiotics used, definition of wound infection, and follow-up rate. [2] The infection rate in our study cohort falls within this range (5%).…”

Section: Discussionmentioning

confidence: 99%

“…Studies on the association of patient's age, number of sutures, length of laceration, presence of diabetes, and wound age with a higher risk of infection have produced conflicting results. [7][8][9][10] Among these factors, wound age has received much more attention. It was believed that there exists a "golden period" beyond which the risk of infection signifi cantly increases, a recent systematic review ruled out the presence of association between any wound age cut off and a higher risk of infection.…”

Section: Discussionmentioning

confidence: 99%

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The risk of wound infection after simple hand laceration

Roodsari

Zahedi

Zehtabchi

2015

World Journal of Emergency Medicine

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BACKGROUND: This prospective observational study aimed to determine the infection rate of simple hand laceration (SHL), and to compare infection rates between patients who were prescribed antibiotics and those who were not. METHODS:The study was performed at two urban hospitals enrolling 125 emergency department (ED) patients with SHL. Exclusion criteria included patients with lacerations for more than 12 hours, immunocompromized patients, patients given antibiotics, and patients with gross contamination, bites or crush injuries. Wound infection was defi ned as clinical infection at a follow-up visit (10-14 days) or wound was treated with antibiotics. Patient satisfaction was also measured using a visual analogue scale 1-10, asking the patients about wound appearance. Demographic data and wound characteristics were compared between the infected and non-infected wounds. The infection rates were also compared between patients who received prophylactic antibiotics and those who did not. The results were presented with medians and quartiles or percentages with 95% confi dence intervals (CI). RESULTS:In the 125 patients with SHL [median age: 28 (18, 43); range: 1-102 years old; 36% female], 44 (35%, 95% CI: 27%-44%) were given antibiotics in the ED. Wound infection was reported in 6 patients (4.8%, 95% CI: 2%-10%). Age, gender, history of diabetes and wound closure were not associated with wound infection (P>0.05). The infection rate was not signifi cantly different between patients with or without antibiotic prophylaxis [7% (3/44), 95% CI: 2%-10% vs. 4% (3/81), 95% CI: 1%-11%, P=0.66]. Patient's satisfaction with appearance of infected and non-infected wounds were signifi cantly different [7.5 (6, 8) vs. 9 (8, 10), P=0.01].CONCLUSION: Approximately 5% of simple hand lacerations become infected. Age, gender, diabetes, prophylactic antibiotics and closure technique do not affect the risk of infection.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The risk of wound infection after simple hand laceration

Roodsari

Zahedi

Zehtabchi

2015

World Journal of Emergency Medicine

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“…The factors affecting infection development are the localization of the wound, duration, depth, configuration and contamination characteristics. [1,2] The presence of a foreign body or visible damp areas. In wounds contaminated with human or animal excretion, infection risk is high despite treatment.…”

Section: Introductionmentioning

confidence: 99%

“…[1,2] Since more devitalized tissue is created in crush wounds inflicted by blunt objects, the risk of infection increases compared to those in inflicted with sharp objects. Although bacterial inoculation development and its amount are related to the time that passes between injury and repair, [1,3] the relationship between wound closure duration and clinical infection is not clear.…”

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confidence: 99%