Abstract:The prediction of the antagonistic activity on the receivers of the Angiotensin II (AII) for diverse compounds, using molecular describers of topologic order calculated with the software DRAGON, allowed generate 81 independent variables. A total of 202 compounds divided in two series was used: one of training that included 176 compounds, with 41 compounds in the active group and 135 in the inactive one; and a second serie of prediction, integrated by 26 compounds, of which 7 are considered active and 19 take p… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.