Prediction of superimposed preeclampsia using uterine artery Doppler velocimetry in women with chronic hypertension

Abstract

The later in pregnancy the abnormal UtA Doppler findings are observed, the greater the risk of preeclampsia. Normalization of UtA Doppler after 25 weeks reduces the risk of preeclampsia to 8%.

Persistence of increased uterine artery resistance in the third trimester and pregnancy outcome

“…Placental invasion is indeed a progressive process, as supported by pathological studies14 and by the gradual fall in uterine artery pulsatility throughout gestation15. Nevertheless, the fate of those who are late normalizers has been subjected to only a few studies5, 6, 16.…”

“…On this basis, how to manage pregnant women if abnormal uterine Doppler is detected in the mid‐trimester is controversial. A reassessment of the uterine circulation later in these pregnancies has been suggested5, 6. It was recently reported that the sequence of changes in uterine flow between the first and second trimesters correlates with the subsequent development of hypertensive disorders and IUGR7.…”

The role of second trimester uterine artery Doppler in pregnancies with systemic lupus erythematosus

“…The exact pathophysiological mechanism through which SLE induces placental damage, possibly leading to PE, is unknown . However, second trimester UtA Doppler prediction of PE has been described to be particularly valuable in pregnancies at high risk of PE due to pre‐existing medical conditions . Despite an increasing and promising move toward the first trimester screening of PE in the general pregnant population, such approach seems less promising in women with high‐risk conditions who would nevertheless already be candidates to intensive monitoring of pregnancy and LDA administration.…”

Uterine artery Doppler velocimetry and obstetric outcomes in connective tissue diseases diagnosed during the first trimester of pregnancy

“…Many authors have studied the predictive role of first trimester UtA Doppler velocimetry both in high risk and unselected populations . Plasencia et al .…”