Prediction of subclinical left ventricular dysfunction with strain rate imaging in patients with asymptomatic severe mitral regurgitation

Lee, Raymond; Hanekom, L.; Marwick, Thomas H.; Leano, Rodel; Wahi, S.

doi:10.1016/j.amjcard.2004.07.129

Cited by 73 publications

(35 citation statements)

References 12 publications

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“…One possible explanation for our finding is that as the global and regional function of the myocardium is related to the number of normally functioning myocytes, conventional echocardiographic parameters may not determine subclinical LV systolic impairment however, L2DS imaging is a recent technical development, and as demonstrated before, is able to measure subclinical myocardial dysfunction [23,24]. Therefore, lower strain and strain rate values in all basal segments may be explained by the direct contact between the mitral apparatus and basal segments, so the rheumatic process can easily extend to these segments which leads to reduced myocardial contraction.…”

Section: Discussionmentioning

confidence: 64%

Prediction of subclinical left ventricular dysfunction with longitudinal two-dimensional strain and strain rate imaging in patients with mitral stenosis

Ongun

Kaya

Özcan

et al. 2009

Int J Cardiovasc Imaging

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Longitudinal two-dimensional strain deformation is a novel technique which evaluates global and regional left ventricular (LV) function with high reproducibility. The aim of the study was to investigate the global and regional systolic function using this method in patients with pure mitral stenosis (MS). Conventional echocardiography and longitudinal two-dimensional strain analysis were performed in 60 patients (41 +/- 5 years, 48 women) with mild to moderate MS (mitral valve area: 1.9 +/- 0.5 cm(2)), and 52 healthy controls (40 +/- 7 years, 37 women). For strain analysis standard apical views were obtained, and by using a software system peak systolic strain and strain rate were calculated off-line in each segment. In all, 88% of the segments could be optimally tracked by the software system. Despite normal LV systolic function as assessed by ejection fraction (66 +/- 8%), mean global longitudinal strain (GLS) and global longitudinal strain rate (GLSR) were significantly reduced in patients with isolated MS (GLS -17 +/- 3.3 vs. -19 +/- 2.5%, P = 0.006 and GLSR -1.3 +/- 0.3 vs. -1.5 +/- 0.3 s(-1), P < 0.0001). Regional analysis demonstrated that patients with MS had a significantly reduced longitudinal peak strain and strain rate in all basal, and some mid (inferior, anteroseptal, interventricular septum) segments of the left ventricle. For other segments longitudinal peak strain and strain rate values were similar among the groups. Evaluation of LV systolic function by longitudinal two-dimensional strain deformation identified early abnormalities in MS patients who had apparently normal standard systolic function.

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Section: Discussionmentioning

confidence: 64%

Prediction of subclinical left ventricular dysfunction with longitudinal two-dimensional strain and strain rate imaging in patients with mitral stenosis

Ongun

Kaya

Özcan

et al. 2009

Int J Cardiovasc Imaging

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“…Although we believe that we have shown the dynamic and progressive nature of MR, we cannot rule out the contribution of late valve scarring from the procedure or the eventual rupture of damaged chordae. Although longitudinal strain and SR were previously shown to be decreased in patients with MR and impaired contractile reserve (18), these parameters were not measured because of technical limitations. We chose to use color tissue-Doppler to measure velocity, strain, and SR, which could also have been reliably measured by two-dimensional derived-speckle tracking imaging.…”

Section: Discussionmentioning

confidence: 99%

Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes

Neilan¹,

Ton-Nu²,

Kawase³

et al. 2008

American Journal of Physiology-Heart and Circulatory Physiology

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“…Previous authors of an angiography study reported 8% venous graft failure at 1 year, 38% at 5 years, and 75% at 10 years after surgery, 8 and progression of the atherosclerotic process in up to 51% 15 years after CABG. 9 The prognosis of this subset of patients, nevertheless, remains doubtful. The Thrombolysis in Myocardial Infarction (TIMI) III ACS subset registry found a similar result during the hospital stay and at 6 months; however, by 1 year the subgroup of patients with a history of CABG had a poorer prognosis (incidence of combined events, 39.3% vs 30.2%; P=.002).…”

Section: Introductionmentioning

confidence: 99%

Can We Improve Outcomes in Patients With Previous Coronary Artery Bypass Surgery Admitted for Acute Coronary Syndrome?

Teixeira

Lourenço

António

et al. 2010

Revista Española de Cardiología (English Edition)

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Prediction of subclinical left ventricular dysfunction with strain rate imaging in patients with asymptomatic severe mitral regurgitation

Cited by 73 publications

References 12 publications

Prediction of subclinical left ventricular dysfunction with longitudinal two-dimensional strain and strain rate imaging in patients with mitral stenosis

Prediction of subclinical left ventricular dysfunction with longitudinal two-dimensional strain and strain rate imaging in patients with mitral stenosis

Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes

Can We Improve Outcomes in Patients With Previous Coronary Artery Bypass Surgery Admitted for Acute Coronary Syndrome?

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