Prediction of Stable High Blood Pressure in Adolescents

Abstract

We studied the relative importance of the initial BP and associated factors in adolescents to predict stable high BP. Out of 17,634 children aged 12-13 yrs an upper group/the upper 5% of the distribution curves for both SBP and DBP/a lower group/10% random from the remainder/were yearly followed for 4 yrs/boys: 1680, girls: 1643/. About 2/3 of children remained at the same percentile point: less than 30% and greater than or equal to 70% of SBP and half of them of DBP distribution. Significant positive tracking correlations were found both for SBP and DBP between the initial BP and follow-up BP readings in the same individual. Stepwise regression analysis showed that the SBP taken at the fourth follow-up can be explained by 29% in boys, 24% in girls on the basis of screening SBP and by 47% in boys, 42% in girls on the basis of SBP measured at the four previous examinations. Using discriminant analysis, 6-9 variables out of 18 studied could correctly allocate adolescents with stable SBP or DBP/less than 70% or greater than or equal to 70% at least 3 examinations/. Our study shows the importance of initial BP and a number of factors associated with stable high BP.

Serum Uric Acid and Blood Pressure in Children at Cardiovascular Risk

“…Although the association between mild hyperuricemia and hypertension has previously been described in several studiesbothinadultsandinchildren, 1,3,4,6,26 a relationship between UA and prehypertension has mainly been reported in adults, 27 with only a few, relatively small studies carried out in children with white coat and borderline hypertension. 4,5,16 …”

“…To fully account for age, gender, and height, according to the tables published in the fourth report on the diagnosis, evaluation, and treatment in children and adolescents, 23 we used BP z-scores rather than raw BP values, which makes our observations more reliable as compared with those of a variety of previous reports. 1,2,4,6,16 Furthermore, to the best of our knowledge, for the first time several clinical and biohumoral variables have been concurrently collected and analyzed in a group of referred children.…”

“…[1][2][3] Preliminary studies have also reported an association between hyperuricemia and nonsustained hypertension, 4,5 and, recently, a relationship between changes in serum UA over time and blood pressure (BP) from childhood to adulthood has been reported. 6 These findings have sparked growing interest in the relationship between UA and BP in children that may lead to pathophysiological insights and greater knowledge on the cause-effect relationship between these factors.…”

Increased Serum Uric Acid Levels Blunt the Antihypertensive Efficacy of Lifestyle Modifications in Children at Cardiovascular Risk

“…15 This rigorous methodological approach makes our observations more reliable as compared with those of a variety of previous reports. 1,6,26,28 Moreover, our study represents one of the few evidences reported in the literature of the effectiveness of an educational program of lifestyle changes in a large cohort of children in a real life context. 20 Finally, there are some limitations to our study.…”

Representative Study for the Evaluation of Age- and Gender-Specific Anthropometric Parameters and Blood Pressure in an Adolescent Hungarian Population

“…In Hungary 25-30% of the adult population is hypertensive. Earlier Környei et al [34,35] and Török et al [36] performed blood pressure screening in a population of children under the age of 14 years, whereas Pá ll et al [37] undertook such measurements in subjects aged between 14 and 18 years in a Hungarian city.…”