“…The proxy modeling optimization has never been found in the literature regarding the CO2-GAGD process. However, the proxy model has been adopted in various reservoir studies and EOR modelings, such as oil production optimization (Badru andKabir , 2003, Zangl et al , 2006), water flooding (Guyaguler et al , 2000, Haghighat Sefat et al , 2014, gas flooding (Ampomah et al , 2016), steam injection, Alkaline-Surfactant-Polymer flooding (Zerpa et al , 2007), SAGD process (Fedutenko et al , 2013a,b, Vanegas Prada and Cunha , 2008, Yang et al , 2011, well locations (White and Royer , 2003), history matching (Goodwin , 2015, He et al , 2016, Zubarev , 2009, etc. The DoE approaches create multiple computer experiments (realizations) for the problem by combining the levels for each parameter.…”