Prediction of Recurrent Events by D-Dimer and Inflammatory Markers in Patients with Normal Cardiac Troponin I (PREDICT) study

Coagulation markers in healthy human subjects exposed to diesel exhaust

“…Data from controlled human DE-exposure models are inconclusive, with one study of a susceptible population [8] unable to demonstrate increased pro-coagulative factors and another, using healthy subjects, suggesting impaired fibrinolysis associated with DE [9]. Cardiovascular death and several associated morbidities are associated with both direct and indirect markers of a "pro-coagulant" state, including those primarily reflecting inflammation (C-reactive protein, CRP) [10], fibrin burden (D-dimer) [11], endothelial injury (von Willebrand's factor, VWF) [12], and inhibition of the fibrinolytic pathway (plasminogen activator inhibitor-1, PAI-1) [13]. Therefore, we used such markers as endpoints to investigate the hypothesis that DE induces a subclinical hyper-coagulable state, as reflected by increases in relevant peripheral blood markers.…”

Novel Protein Markers of Acute Coronary Syndrome Complications in Low-Risk Outpatients: A Systematic Review of Potential Use in the Emergency Department

“…In some cases, data were sufficient for some, but not all of the markers studied in a single publication (11,14,16,17 ). In 3 publications, data were insufficient for all markers reported in this study (18,19,22 ). The authors of these manuscripts were contacted for these data, and data were provided by 3 authors for an additional 9 markers.…”

Assessment of markers of thrombin generation in patients with acute myocardial infarction complicated by ventricular fibrillation

“…10 Indicators of coagulation activation are also 167 Abbreviations: CHD = coronary heart disease, MI = myocardial infarction, VF = ventricular fibrillation. Table I. found to be useful for predicting future cardiovascular events, such as myocardial reinfarction or death.…”