Prediction of Preeclampsia by Measuring of Mean Platelet Volume and Platelet Distribution Width

Mahmoud, Mahmoud; elshabrawi, ali; Khalifa, Naglaa Ali; Ibrahim, Safaa A.

doi:10.21608/zumj.2020.25158.1762

Cited by 1 publication

(2 citation statements)

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“…MPV was significantly increased in group I than group II at 20, 24, 28, 32, 36 and 37 weeks. This was in line with Mahmoud et al [15] who showed that the MPV was higher in preeclampsia patients.…”

Section: Discussionsupporting

confidence: 91%

“…At cut-off >10.4 of PDW to predict PE, sensitivity was 88.89, specificity was 54.95, PPV was 16.3, NPV was 98.0, AUC was 0.764 and P value was 0.002. This was in line with Tesfay et al (2019) [7] who found that PDW can differentiate NT pregnant women from preeclamptic pregnant women at a cut off value >10.85fl with sensitivity of 72.2%, specificity of 52.1%, PPV of 46.0 %, NPV of 76.8% and AUC (0.625).This wasn't in line with Mahmoud et al (2020) [15] who showed that the PDW was higher in preeclampsia patients and the cut-off value of PDW was above 17.7, it showed a high specificity of 93.3% and a sensitivity of 96% with a p < 0.0001.…”

Section: Discussionsupporting

confidence: 75%

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The Role of Platelet Indices in Prediction of Pre-eclampsia

Elbasuony

Hodeib

Eljejawy

et al. 2021

JAMMR

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Objective: The aim of this work is to investigate the diagnostic value of platelet count (PC), mean platelet volume (MPV), the PC to MPV ratio and platelet distribution width (PDW) for prediction of pre-eclampsia (PE). Subjects and Methods: This prospective cohort study included 100 pregnant women, in the ﬁrst trimester of pregnancy attending to University Hospital, Obstetric Outpatient Clinic, for routine obstetric care from January 2019 to December 2019. Routine obstetric follow-up consists of monthly visits until 32nd gestational week, bimonthly visits between 32nd and 36th gestational week, and weekly thereafter. Patients were classified into two groups: group I: 9 pre-eclamptic patients and group II: non pre-eclamptic 91 patients. CBC indices were measured at each planned visit Results: PC, PC/MPV were significantly decreased, MPV and PDW were significantly increased in group I than group II at the 2nd part of pregnancy. To predict pre-eclampsia, PC at cut-off ≤214, sensitivity was 77.78, specificity was 76.92. MPV at cut-off >9.7, sensitivity was 77.78, specificity was 100.00, PC-MPV at cut-off ≤26.89, sensitivity was 88.89, specificity was 78.02. PDW at cut-off >10.4, sensitivity was 88.89, specificity was 54.95. Conclusion: The increase in the MPV and PDW and the decrease in PC and PC/MPV were observed in preeclampsia. Thus, the platelet indices which are easily available, as well as economical, can also be used in the prediction and early diagnosis of preeclampsia.

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Section: Discussionsupporting

confidence: 91%