Prediction of Postoperative Lung Function in Patients Undergoing Lung Resection

Abstract

Dual-energy perfusion CT was more accurate than perfusion scintigraphy was for predicting postoperative lung function.

Efficacy of Bronchoscopic Lung Volume Reduction by Endobronchial Valves in Patients with Heterogeneous Emphysema: Report on the First Asian Cases

“…The use of CT scan is important in selecting patients with heterogeneous emphysema and for identifying fissure integrity. Unlike other studies, we performed pre-procedure dual-energy perfusion CT instead of ventilation-perfusion scintigraphy in all patients to identify the target lobe (11, 24), which was defined as the most hyperinflated and least perfused lobe in our study. In addition to dual-energy perfusion CT, we performed a balloon occlusion test (Chartis® Pulmonary Assessment System) to confirm that the target lobe had no collateral ventilation prior to insertion of the valve.…”

“…The perfusion to volume ratio of each lobe was calculated by measuring the iodine to voxel ratio with in-house software. The detailed CT protocol was described in other paper (11). The most hyperinflated and least perfused lobe of the emphysematous lung was selected as the target lobe for BLVR.…”

Bronchoscopic lung volume reduction by endobronchial valve in advanced emphysema: the first Asian report

“…The perfusion-to-volume ratio of each lobe was calculated by quantitatively measuring the increased CT density caused by iodine in each voxel of each lobe using the in-house software. 22 , 23 The target lobe was selected on the basis of these CT data (ie, the most hyperinflated and the least perfused lobe) after discussions between a pulmonologist and two radiologists ( Figure 1 ).…”

Generation of ventilation/perfusion ratio map in surgical patients by dual-energy CT after xenon inhalation and intravenous contrast media

“…Pulmonary function test (PFT) using spirometry is the current standard method of evaluating pulmonary function. While many studies have evaluated the change in lung volume before and after lung resection and correlated this with pulmonary function test results [ 1 – 3 ], there is very little evidence on the changes in ventilation perfusion ratio (V/Q) before and after lung resection. This is considered to be at least in part due to the practical difficulty of frequently performing ventilation perfusion scans using radioneuclides, as well as its low spatial resolution.…”

“…Furthermore we have correlated these results with pulmonary function tests and also studied its application for the detection of response to therapeutic agents for chronic obstructive pulmonary disease [ 7 ]. Also, dual-energy CT allows extraction of the iodine component from the enhanced lung parenchyma according to the material decomposition theory [ 3 ]. This enables three dimensional acquisition of the pulmonary perfusion.…”