Prediction of long-term functional outcome in patients with acute ischemic non-embolic stroke

Protopsaltis, John; Kokkoris, Stelios; Korantzopoulos, Panagiotis; Milionis, Haralampos; Karzi, Efthalia; Anastasopoulou, Alexandra; Filioti, Kostantina; Antonopoulos, Stavros; Μelidonis, Αndreas; Giannoulis, Gregory

doi:10.1016/j.atherosclerosis.2008.05.042

Cited by 40 publications

(24 citation statements)

References 30 publications

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“…However, few clinical studies have made use of their level as stroke biomarkers. IL-1β levels mostly were associated with poor long-term functional outcome in study, [106] while IL-1Ra levels have shown to be predictive of the development of post-stroke infections. [107] Transforming growth factor beta Transforming growth factor beta (TGF-β) proteins are multifunctional cytokines with pleiotropic functions.…”

Section: Il-1βmentioning

confidence: 84%

Role of neuroinflammation in ischemic stroke

Li¹,

Pan²,

Tang³

et al. 2017

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Ischemic stroke causes the depletion of energy and induce excitotoxicity and neuroinflammation in the brain that results from thrombotic blockage. Neuroinflammation occurs initially depending on activated resident microglia that has the same function as the macrophage. Activated microglia participates in the neuroinflammatory process by phagocytosing the injured brain cells and producing the pro-and anti-inflammatory mediators. In this review, the authors present an overview of the role of microglia in mediating neuroinflammation in ischemic stroke. Key words:Microglia, ischemic stroke, neuroinflammation ABSTRACT Topic: StrokeThis is an open access article distributed under the terms of the Creative Commons AttributionNonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Section: Il-1βmentioning

confidence: 84%

Role of neuroinflammation in ischemic stroke

Li¹,

Pan²,

Tang³

et al. 2017

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“…2,[18][19][20][21][22][23][24][25] Younger age consistently predicts favorable ADL outcome, defined as an MRS 2 or a BI !95. 2,19-21,24-26 A lower score on NIHSS at admission (<10) predicts a favorable outcome; however, the closer the NIHSS is to zero, the better the prediction of independence.…”

Section: Activities Of Daily Livingmentioning

confidence: 99%

“…2 Other less consistently reported clinical predictors of long-term ADL independence include urinary continence, good sitting balance, absence of aphasia, and absence of diabetes mellitus. 20,24,26,28,29 Diabetic patients, especially those who are older, face a higher risk of severe stroke leading to worse outcome. 24 No other medical comorbidities have been associated with functional outcome.…”

Section: Activities Of Daily Livingmentioning

confidence: 99%

“…20,24,26,28,29 Diabetic patients, especially those who are older, face a higher risk of severe stroke leading to worse outcome. 24 No other medical comorbidities have been associated with functional outcome. 2 Jongbloed 26 noted in a systematic review that longer time before hospital admission was associated with worse functional ability at discharge, suggesting that earlier hospital arrival provided for more effective acute treatment.…”

Section: Activities Of Daily Livingmentioning

confidence: 99%

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Predictors of Functional Outcome Following Stroke

Harvey

2015

Physical Medicine and Rehabilitation Clinics of North America

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“…En cuanto a la marcha, el pronóstico es bastante bueno, de manera que 70% a 80% de los pacientes vuelven caminar, pero solo el 30% a 50 % retornan a la deambulación en la comunidad 16 .…”

Section: Discussionunclassified

Hemorragia intracraneal espontánea durante el puerperio: estudio de caso

Báez¹,

Maestre²,

Guevara³

et al. 2017

Rev Col Med Fis Reh

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RESUMENLa cefalea es un hallazgo frecuente en el periodo posparto por causas multifactoriales, siendo una de ellas, aunque no la más frecuente, la hemorragia intracraneal espontánea (HIE). Esta etiología tiene diferentes tasas de incidencia de acuerdo con la población tratada, con causas claramente establecidas en puerperio como lo son la ruptura de aneurisma y/o malformaciones vasculares. Presentamos el caso de una mujer puérpera joven, sin antecedentes de importancia, quien consulta al servicio de urgencias por cefalea, con estudios iniciales aparentemente normales, sin factores de riesgo importantes como presencia de hipertensión arterial, con posterior progresión a una HIE, descartando de forma inicial las causas más frecuentes para estos casos. El siguiente estudio de caso busca encontrar posibles etiologías de menor prevalencia que se ajusten con el cuadro de la paciente, además de factores pronósticos en el momento de realizar el proceso de rehabilitación. Palabras clave: Posparto, hemorragia intracerebral, hemorragia subaracnoidea, ataque cerebrovascular hemorrágico, rehabilitación, factores predictivos de funcionalidad. ABSTRACTHeadache is a frequent finding in the postpartum period due to multifactorial causes, one of them, although not the most frequent one, is spontaneous intracranial hemorrhage (HIE). This etiology has different incidence rates according to the treated population, with clearly established causes in the puerperium such as aneurysm rupture and / or vascular malformations. We present the case of a young puerperal woman, without important antecedents, who consults with the emergency department with headache, with apparently normal initial studies, without important risk factors like presence of arterial hypertension, with progression to an HIE, initially discarding the causes more frequent for these cases. The following case study seeks to find possible etiologies of lower prevalence that fit with the patient's condition, in addition to prognostic factors at the time of the rehabilitation process.

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Prediction of long-term functional outcome in patients with acute ischemic non-embolic stroke

Cited by 40 publications

References 30 publications

Role of neuroinflammation in ischemic stroke

Role of neuroinflammation in ischemic stroke

Predictors of Functional Outcome Following Stroke

Hemorragia intracraneal espontánea durante el puerperio: estudio de caso

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