Prediction of idiopathic respiratory distress syndrome by the stable microbubble test on gastric aspirate

Teeratakulpisarn, Jamaree; Taksaphan, Sukanya; Pengsaa, Krisana; Wiangnon, Surapon; Kosuwon, Weerachai

doi:10.1002/(sici)1099-0496(199806)25:6<383::aid-ppul5>3.0.co;2-i

Cited by 18 publications

(7 citation statements)

References 17 publications

(26 reference statements)

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“…Some studies suggest that SMT in the gastric fluid is an accurate test for the diagnosis of RDS, given cutoff points of 10 to 20 SMB/mm 2 [5,7,8,17] In this study, we observed that the majority of term or near term infants with respiratory distress had a low SMB count and that the vast majority of infants without respiratory distress had high SMB counts, using the best cutoff point of 35 SMB/mm 2 (sensitivity of 75%, specificity of 94%).…”

Section: Discussionmentioning

confidence: 99%

“…The stable microbubble test (SMT), developed by Pattle et al [14] in 1979, gained renewed interest in the surfactant therapy era as it has been shown that it is an accurate test to discriminate surfactant-deficient preterm infants who develop respiratory distress syndrome (RDS), when performed in amniotic fluid [4,5,14], gastric aspirates [5,7,8,17] or tracheal aspirates [2,9]. It has been suggested that it could be used to select patients for surfactant therapy; however, the SMT has not been employed in a controlled way so as to explore the possible role of surfactant deficiency or dysfunction in other respiratory conditions such as TTN.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of surfactant function at birth determined by the stable microbubble test in term and near term infants with respiratory distress

et al. 2004

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of surfactant function at birth determined by the stable microbubble test in term and near term infants with respiratory distress

et al. 2004

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“…Teeratakulpisarn et al 8 realizaram o teste com aspirado gástrico de recém-nascidos, utilizando um ponto de corte de 20 microbolhas estáveis por milímetro quadrado (mbe/mm²), e encontraram sensibilidade e especificidade em torno de 95% e valor preditivo negativo acima de 99% para identificar recém-nascidos com deficiência de surfactante.…”

Section: Discussionunclassified

Teste das microbolhas estáveis no líquido amniótico de recém-nascidos prematuros para predição da maturidade pulmonar

Pereira¹,

Luz²,

Rivero³

et al. 2018

Arch Health Invest

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Introdução À medida que o tratamento profilático ou precoce com surfactante mostrou-se vantajoso nos recém-nascidos prematuros com imaturidade pulmonar renovou-se o interesse na busca de testes diagnósticos nesta área. Objetivo Avaliar o desempenho do TME no aspirado gástrico, na predição da síndrome do desconforto respiratório (SDR) em recém-nascidos prematuros. Material e Método: Foi coletado aspirado gástrico em partos prematuros ocorridos no Hospital Geral Dr. César Cals (HGCC), no período compreendido entre julho de 2015 a julho de 2017 e realizado o TME nesse material. Resultados A idade média dos recém-nascidos foi de foi de 30,02 ± 1,98 semanas e a média do peso e o desvio padrão foi 2019,50 ± 573,2 gramas. Considerando-se importâncias iguais para sensibilidade e especificidade, o corte de melhor desempenho para o TME foi de 9 μb/mm2. Levando em consideração esse ponto de corte, a sensibilidade encontrada foi de 100% (IC 95%: 96 -100) e a especificidade de 90% (IC 95%: 68-99). Conclusão: O TME no aspirado gástrico de prematuros tem alta sensibilidade e especificidade para predizer a SDR. O valor da sensibilidade encontrado neste estudo (100%) foi o maior já relatado na literatura mundial, levando-se em consideração a utilização de apenas um único teste (TME) em diferentes amostras. O TME no aspirado gástrico apresenta um excelente desempenho para predizer a SDR, similar aos demais testes mais sofisticados descritos na literatura, como por exemplo, a contagem de corpos lamelares.Descritores: Técnicas e Procedimentos Diagnósticos; Proteínas Associadas a Surfactantes Pulmonares; Líquido Amniótico; Recém-Nascido Prematuro.

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“…The diagnosis of RDS in newborn was made based on the clinical and radiological criteria. The clinical diagnosis of RDS was made with the presence of at least two of the following clinical signs manifesting within 6 hours after birth and persisted for 24 hours or more: 2,8,9 • Respiratory rate > 60/min • Expiratory grunting • Chest retraction or cyanosis The radiological diagnosis of RDS was made if features suggestive of RDS (hypo aeration, diffuse reticulogranular pattern with air bronchogram, ground glass appearance) were seen in Chest X-Ray taken 6 hours after birth.…”

Section: Criteria For Diagnosis Of Rds In Newbornmentioning

confidence: 99%

Comparison of Reliability of Tap Test and Shake Test for Determination of Fetal Lung Maturity

Bajracharya

2014

Nepal j. obstet. gynaecol.

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Aims: To compare the reliability of tap test and shake test for determination of fetal lung maturity in pregnant women between 28 weeks and 36 completed week’s gestation either with preterm prelabour rupture of membrane or preterm labour. Methods: Amniotic fluid samples from vaginal pool were obtained from one hundred pregnant women who met the inclusion criteria. Both tap test and shake test were performed in each sample. All deliveries occurred within 72 hours of collection of amniotic fluid. The results of the tests were compared with the incidence of neonatal respiratory distress syndrome. Results: Out of 100 tests performed, tap test predicted 17% as immature and 83% as mature and shake test predicted 51% as immature and 49% as mature. Among 100 newborns, 9 (9%) were found to be true immature as they developed respiratory distress syndrome. The sensitivity, specificity, predictive value for fetal lung immaturity and maturity by tap test was 88.9%, 90.1%, 47.1% and 98.8% respectively and the sensitivity, specificity, predictive value for fetal lung immaturity and maturity by shake test was 100%, 53.8%,17.6% and 100% respectively. Conclusions: In view of very low specificity and predictive value for fetal lung immaturity by shake test compared to that by tap test and lower sensitivity of the tap test than the shake test, neither of the tests is reliable than the other and these two tests can not replace each other DOI: http://www.dx.doi.org/10.3126/njog.v7i2.11141 Nepal Journal of Obstetrics and Gynaecology / Vol 7 / No. 2 / Issue 14 / July-Dec, 2012 / 36-39

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Prediction of idiopathic respiratory distress syndrome by the stable microbubble test on gastric aspirate

Cited by 18 publications

References 17 publications

Evaluation of surfactant function at birth determined by the stable microbubble test in term and near term infants with respiratory distress

Evaluation of surfactant function at birth determined by the stable microbubble test in term and near term infants with respiratory distress

Teste das microbolhas estáveis no líquido amniótico de recém-nascidos prematuros para predição da maturidade pulmonar

Comparison of Reliability of Tap Test and Shake Test for Determination of Fetal Lung Maturity

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