Abstract:In patients with heart failure, atrial septal defect (ASD) closure has a risk to induce life-threatening acute pulmonary edema. The objective of this study was to develope a novel framework for quantitative prediction of hemodynamics after ASD closure. The generalized circulatory equilibrium comprises right and left cardiac output (CO) curves, and pulmonary and systemic venous return surfaces. We incorporated ASD into the framework of circulatory equilibrium by representing ASD shunt flow (QASD) by the differe… Show more
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