Prediction of flap necrosis with laser induced indocyanine green fluorescence in a rat model

Intraoperative indocyanine green fluorescence angiography to predict wound complications in complex ventral hernia repair

“…Over the last decade, ICG-FA has been applied to numerous fields of surgery including cardiovascular intraoperative graft evaluation [17,18], solid organ transplant graft perfusion [19,20], and ophthalmologic evaluation of chorioretinal disorders [21]. It has been suggested to be beneficial in the intraoperative evaluation of skin and soft tissue reconstruction, particularly in breast reconstruction, with the ability to evaluate tissue perfusion, detect skin perforators, predict skin flap necrosis and loss, and prevent complications of wound healing [22][23][24][25][26][27][28][29].…”

Mass spectrometric characterization of limited proteolysis activity in human plasma samples under mild acidic conditions

“…by an implantable Doppler system [31], by color duplex sonography [32][33][34][35][36][37] near-infrared spectroscopy [38,39], microdialysis [40][41][42], and laser Doppler flow metry [43]. Indocyanine green (ICG) angiography has been used in the evaluation of flap perfusion and is now in the clinical testing phase although costs for this method are fairly high [44][45][46]. Also blood glucose measurements were suggested for flap monitoring and for establishing a simple method that can be widely applied [6,47].…”

Is indocyanine green angiography a reliable tool for the assessment of venous congestion in muscle flaps?

“…After the administration of ICG, the compound absorbs photons at 806 nm, thus exciting ICG electrons which emit photons at a lower energy and longer wavelength. The camera then captures the emitted photons [15,20] . ICG angiography used in this case was performed per SPY Elite protocol with 3 mL dose of ICG solution (ICG 2.5 mg/mL in saline diluent) administered intravenously.…”

“…Several methods have already been utilized in an attempt to achieve this goal. These include continuous polarographic tissue oxygen tension monitoring, laser Doppler flowmetry (LDF), tissue pH monitoring and indocyanine green (ICG) near-infrared video angiography [7][8][9][10][11][12][13][14][15] . ICG angiography has popularly become a commonly used technique to measure vascular perfusion of flaps.…”