Prediction of Early Development of Chronic Nonrheumatic Atrial Fibrillation.

Sakamoto, Hironosuke; Okamoto, Eiichi; Imataka, Kouji; Ieki, Keiko; Fujii, Jun

doi:10.1536/ihj.36.191

Cited by 26 publications

(13 citation statements)

References 27 publications

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“…In Japan, age, left atrial diameter, prior myocardial infarction, valvular heart disease, and diabetes mellitus have been reported as independent risk factors for the progression to persistent/permanent AF. 53, 54 In Western countries, the HATCH score (hypertension, age [75 years and older], transient ischemic attack or stroke, chronic obstructive pulmonary disease and heart failure) is used to predict the progression to permanent AF. 55 Patients with poor QOL due to paroxysmal AF should be treated with antiarrhythmic drugs to prevent episodes of AF.…”

Section: Paroxysmal Afmentioning

confidence: 99%

Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2013)

2014

Circ J

378

130

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Section: Paroxysmal Afmentioning

confidence: 99%

Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2013)

2014

Circ J

378

130

View full text Add to dashboard Cite

“…Independent risk factors for progression to persistent AF appeared to be age, left atrial diameter, history of myocardial infarction, and valvular disease in a study using multivariate analysis, 65 and age, left atrial diameter, heart failure, diabetes mellitus, cardiothoracic ratio, f wave amplitude in lead V1, and left ventricular ejection fraction in a study using univariate analysis. 66 Patients with poor QOL due to paroxysmal AF should be treated with antiarrhythmic drugs to prevent episodes of AF. However, the duration of pharmacotherapy needed to maintain sinus rhythm should be determined for individual patients based on comprehensive evaluation of the duration of treatment, background characteristics, and feasibility of non-pharmacological treatment with catheter ablation.…”

Section: Paroxysmal Afmentioning

confidence: 99%

Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2008) - Digest Version -

Group¹

2010

Circ J

121

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“…4) Factors related to the development of permanent AF have been reported. 2,[5][6][7] A number of recent studies 3,[8][9][10][11] have associated AF and its treatment with quality-of-life issues.…”

Section: Discussionmentioning

confidence: 99%

Symptoms of Atrial Fibrillation in Patients With and Without Subsequent Permanent Atrial Fibrillation Based on a Retrospective Questionnaire Survey

Kawara¹,

Narumi

Hirao

et al. 2010

Int. Heart J.

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SummaryThe aim of the present study was to determine whether symptoms of atrial fibrillation (AF) differ between patients with and without subsequent permanent AF. Sixty-four patients (68 ± 10 years old, 45 males) were recruited. AF followup was started at the age of 61 ± 10 years and accomplished in a median period of 4.9 years (396 person-years). Permanent AF, defined as lasting > 180 days, developed in 17 patients (14 males) (43 per 1000 person-years). The AF followup period was longer in the permanent AF group than in the non-permanent AF group (median, 9.8 versus 4.2 years, P < 0.001). For baseline characteristics, hypertension was less frequent in the permanent AF group than in the nonpermanent AF group (18% versus 45%, P < 0.05). A retrospective questionnaire survey regarding initial AF symptoms was conducted. The severity of AF symptoms by a 4-grade scale was significantly milder in the permanent AF group than in the nonpermanent AF group (P < 0.05). Cox proportional hazards model analysis revealed that the severity of initial AF symptoms was related to the subsequent development of permanent AF (hazard ratio 0.46 per grade, 95% confidence interval 0.23 -0.93, P < 0.05), but age, gender, hypertension, diabetes mellitus, organic heart disease, and left atrial dimension were not. The permanent AF-free rate was significantly lower in 33 patients with mild symptoms than in 31 patients with severe symptoms (log-rank test, P < 0.05). These results point to an inconspicuous feature in the development of permanent AF. (Int Heart J 2010; 51: 242-246) Key words: Arrhythmia, Heart failure, Hypertension, Susceptibility T he severity of symptoms is quite an important factor for determining the prognosis of patients with organic heart disease. The New York Heart Association classification of cardiac performance is clearly related to subsequent cardiac events. Syncope is a risk factor for sudden cardiac death in patients with a Brugada-type electrocardiogram. As a consequence, symptoms affect the treatment of such diseases. Atrial fibrillation (AF) causes variable symptoms, from mild which are subclinical, to severe requiring emergency care. Very slightly symptomatic AF is allowed and left; by contrast, severely symptomatic AF requires intensive therapies to restore or maintain sinus rhythm. AF usually occurs in a paroxysmal or persistent form, and then develops into a permanent form when the feasibility of restoring sinus rhythm becomes extremely low.1,2) We believe that patients' perceptions of their symptoms may be associated with the course of AF. To clarify whether the symptoms of AF differ between patients with and without subsequent development of permanent AF, a retrospective questionnaire survey was carried out. MethodsEthical issues: The study was conducted in accordance with Good Clinical Practice guidelines and the Declaration of Helsinki. The study protocol and written subject information were reviewed and approved by the ethics committee of Tokyo Medical and Dental University. Sixty-four patients (68 ±...

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Prediction of Early Development of Chronic Nonrheumatic Atrial Fibrillation.

Cited by 26 publications

References 27 publications

Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2013)

Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2013)

Guidelines for Pharmacotherapy of Atrial Fibrillation (JCS 2008) - Digest Version -

Symptoms of Atrial Fibrillation in Patients With and Without Subsequent Permanent Atrial Fibrillation Based on a Retrospective Questionnaire Survey

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