Prediction of Coronary Heart Disease by Erectile Dysfunction in Men Referred for Nuclear Stress Testing

Min, James K.; Williams, Kim A.; Okwuosa, Tochi M.; Bell, George W.; Panutich, Michael; Ward, R. Parker

doi:10.1001/archinte.166.2.201

Cited by 63 publications

(46 citation statements)

References 36 publications

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“…6,10,17,18 It is uncertain how many of the patients in our study with ED had subclinical cardiovascular disease, and if they should have been screened for cardiovascular disease.…”

Section: Resultsmentioning

confidence: 99%

“…21 The overall ED prevalence in men with coronary artery disease seems to be high. 17,22 ED prevalence in acute coronary syndrome was found to differ according to the extent of coronary artery disease, with a higher prevalence in patients with worse atherosclerosis. Coronary atherosclerosis seems to be more severe in patients with ED.…”

Section: Introductionmentioning

confidence: 97%

“…Coronary atherosclerosis seems to be more severe in patients with ED. 17,23 It has also been demonstrated in several prospective studies that ED can be predictive of coronary heart disease, cardiovascular events and death in patients with diabetes mellitus specifically. 7,8,24 Since it has been suggested that ED might be an early symptom of generalised cardiovascular disease, patients should probably be systematically screened for ED as part of periodic examination programmes.…”

Section: Introductionmentioning

confidence: 98%

“…There seems to be a strong link between ED and atherosclerotic vascular disease. 6,10,17,18 Endothelial dysfunction is the common underlying factor linking ED with cardiovascular disease. [19][20][21] This plays an important role in the development of atherosclerosis and systemic vascular diseases, such as diabetes mellitus, hypertension, dyslipidaemia, ischaemic heart disease, strokes and claudication.…”

Section: Introductionmentioning

confidence: 99%

“…21,22 ED can be an early marker for atherosclerosis, cardiovascular risk and subclinical vascular pathology. 17,19,20,23 It can also be predictive of the presence and extent of subclinical atherosclerosis, independent of traditional risk factors. 21 The overall ED prevalence in men with coronary artery disease seems to be high.…”

Section: Introductionmentioning

confidence: 99%

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The prevalence and associations of erectile dysfunction in a South African male diabetic urban population

Kemp

Rheeder

2015

Journal of Endocrinology, Metabolism and Diabetes of South Afri

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Background: Erectile dysfunction (ED) is a common condition in patients with type 1 or type 2 diabetes mellitus. The prevalence and predictors in our patient population are unknown since minimal data exist for this condition in South Africa. Method: An observational, cross-sectional study was performed on 150 consecutive male patients aged ≥ 50 years, with either type 1 or type 2 diabetes mellitus, attending the Steve Biko Academic Hospital Diabetes Clinic. These patients were evaluated for diabetes mellitus control and medical complications, and for the presence of ED. Morning serum testosterone levels were determined. Results: Some degree of ED was reported in 95% of the patients, with 51% reporting serious dysfunction. Using multivariate logistic regression, it was determined that the significant factors associated with ED were age, body mass index, the peripheral neuropathy score and diuretic therapy. Differences in quality-of-life scores were seen in some ED subgroups. Conclusion: This study confirms the high prevalence of ED in diabetic male patients in a tertiary setting. It is suggested that universal screening should be performed for this population group. Multiple predictors of ED were identified in this study. ED negatively affected quality of life, but not in a statistically significant way.

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“…6,10,17,18 It is uncertain how many of the patients in our study with ED had subclinical cardiovascular disease, and if they should have been screened for cardiovascular disease.…”

Section: Resultsmentioning

confidence: 99%