Abstract-Creating the best solution in terms of a rehabilitation technique, device or system design for rehabilitation medicine interventions or assistance is not enough. The new solution has to be effective. And, in order to be effective, it has to be used therefore, the solution has to be accepted by the user as a solution for his/her functional need. The solution must convince the physical therapist, all the other members of the medical team, as well as the patient and his/her family, of its utility, before use and during its use. The degree of usability of the solution will be cultural specific and very personal. A model for Rehabilitation Technology Acceptance and Usability (RTAU) has been developed in order to become a base for rehabilitation technology usability prediction. The model presented in this paper is a world-wide premiere, considering the patient centered approach.