Prediction of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage using jugular bulb oximetry monitoring: preliminary results

Souissi, R; Boubakker, A; Souissi, Hatem; Abdel-Razek, Ahmed; Badri, Marwan; Bziouech, S; Jemel, Hafedh

doi:10.1186/cc8575

Cited by 3 publications

(2 citation statements)

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“…Meanwhile, TCD became standard in the intensive care evaluation of aSAH patients. Souissi et al used jugular bulb oximetry monitoring and found increased cerebral oxygen extractions (AVDO2) 12 h before the significant vasospasm occurred clinically [36]. Similar results were achieved in a study by Heran et al [37].…”

Section: Discussionmentioning

confidence: 55%

Could Phosphorous MR Spectroscopy Help Predict the Severity of Vasospasm? A Pilot Study

Galijasevic,

Steiger,

Treichl

et al. 2024

Diagnostics

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One of the main causes of the dismal prognosis in patients who survive the initial bleeding after aneurysmal subarachnoidal hemorrhage is the delayed cerebral ischaemia caused by vasospasm. Studies suggest that cerebral magnesium and pH may potentially play a role in the pathophysiology of this adverse event. Using phosphorous magnetic resonance spectrocopy (31P-MRS), we calculated the cerebral magnesium (Mg) and pH levels in 13 patients who suffered from aSAH. The values between the group that developed clinically significant vasospasm (n = 7) and the group that did not (n = 6) were compared. The results of this study show significantly lower cerebral Mg levels (p = 0.019) and higher pH levels (p < 0.001) in the cumulative group (all brain voxels together) in patients who developed clinically significant vasospasm. Further clinical studies on a larger group of carefully selected patients are needed in order to predict clinically significant vasospasm.

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Section: Discussionmentioning

confidence: 55%

Could Phosphorous MR Spectroscopy Help Predict the Severity of Vasospasm? A Pilot Study

Galijasevic,

Steiger,

Treichl

et al. 2024

Diagnostics

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“…Cerebral hemorrhage is a cause of cerebral brain vasospasm ( Souissi et al, 2010 ). More importantly, subarachnoid hemorrhage (SAH) results in long-term cognitive and neurological outcomes ( Bederson et al, 2009 ; Suzuki 2015 ).…”

Section: Protective Effects Of Res On Cvdmentioning

confidence: 99%

Antioxidant and neuroprotective actions of resveratrol in cerebrovascular diseases

Wang

Qian²,

Wu³

2022

Front. Pharmacol.

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Cerebralvascular diseases are the most common high-mortality diseases worldwide. Despite its global prevalence, effective treatments and therapies need to be explored. Given that oxidative stress is an important risk factor involved with cerebral vascular diseases, natural antioxidants and its derivatives can be served as a promising therapeutic strategy. Resveratrol (3, 5, 4′-trihydroxystilbene) is a natural polyphenolic antioxidant found in grape skins, red wine, and berries. As a phytoalexin to protect against oxidative stress, resveratrol has therapeutic value in cerebrovascular diseases mainly by inhibiting excessive reactive oxygen species production, elevating antioxidant enzyme activity, and other antioxidant molecular mechanisms. This review aims to collect novel kinds of literature regarding the protective activities of resveratrol on cerebrovascular diseases, addressing the potential mechanisms underlying the antioxidative activities and mitochondrial protection of resveratrol. We also provide new insights into the chemistry, sources, and bioavailability of resveratrol.

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Could Phosphorous MR Spectroscopy Help Predict the Severity of Vasospasm? A Pilot Study

Galijasevic,

Steiger,

Treichl

et al. 2024

Preprint

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One of the main causes of the dismal prognosis in patients who survive the initial bleeding after aneurysmal subarachnoidal hemorrhage is the delayed cerebral ischaemia caused by vasospasm. Studies suggest that cerebral magnesium and pH may potentially play a role in the pathophysiology of this adverse event. Using phosphorous magnetic resonance spectrocopy (31P-MRS) we calculated the cerebral magnesium (Mg) and pH level in 13 patients who suffered aSAH. The values between the group that developed clinically significant vasospasm (n=7) and the group that did not (n=6) were compared. The results of this study showed significantly lower cerebral Mg levels (p=0.019) and higher pH (p&lt;0.001) in cumulative group (all brain voxels together) in patients who developed clinically significant vasospasm. Further clinical studies on a larger group of carefully selected patients are needed in order to predict clinically significant vasospasm.

show abstract

Prediction of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage using jugular bulb oximetry monitoring: preliminary results

Cited by 3 publications

References 0 publications

Could Phosphorous MR Spectroscopy Help Predict the Severity of Vasospasm? A Pilot Study

Could Phosphorous MR Spectroscopy Help Predict the Severity of Vasospasm? A Pilot Study

Antioxidant and neuroprotective actions of resveratrol in cerebrovascular diseases

Could Phosphorous MR Spectroscopy Help Predict the Severity of Vasospasm? A Pilot Study

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