2018
DOI: 10.1001/jamainternmed.2018.3131
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Prediction of Cardiovascular Risk to Guide Primary Prevention

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Cited by 4 publications
(2 citation statements)
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“…CVD is the leading cause of death worldwide and a major public health concern. Its risk assessment is crucial to many existing treatment and control guidelines [14][15][16] . Although the effect of primary health care in controlling CVD has been demonstrated before, controversies still exist on the benefits of applying risk prediction compared with those of the risk factor approach in population-based interventions 17,18 .…”
Section: Discussionmentioning
confidence: 99%
“…CVD is the leading cause of death worldwide and a major public health concern. Its risk assessment is crucial to many existing treatment and control guidelines [14][15][16] . Although the effect of primary health care in controlling CVD has been demonstrated before, controversies still exist on the benefits of applying risk prediction compared with those of the risk factor approach in population-based interventions 17,18 .…”
Section: Discussionmentioning
confidence: 99%
“…11,12 Based on the increased prevalence of subclinical coronary artery disease demonstrated in masters endurance athletes with low conventional risk-factor profiles, coronary artery calcium scores are recommended over conventional calculators as an independent predictor of cardiac events to guide use of additional measures for primary prevention. [13][14][15][16] The inverse correlation of coronary artery plaque volume with short-term cardiac event-free survival, and documentation of coronary atherosclerosis as the cause of race-related sudden cardiac deaths even in the most experienced runners attest to the morbidity and mortality associated with what has been called by some "hearts of stone" of undetermined significance. [17][18][19][20][21][22][23] An explanation for increased coronary atherosclerosis in experienced endurance athletes compared with matched control persons is that inflammation during repetitive bouts of exertional rhabdomyolysis promotes calcification through recurrent injury to vascular endothelium.…”
mentioning
confidence: 99%