Prediction and validation of circulating G-quadruplexes as a novel biomarker in colorectal cancer
Hui Zhang,
Jing Zhou,
Yingjiang Ye
Abstract:Background
There are some problems in the clinical diagnosis of colorectal cancer (CRC), such as the difficulty in saving samples, so it is the most popular research work to develop a diagnostic index and method that is easy to obtain, convenient to save and stable. G-quadruplex (G4) is a unique structure found in DNA and it plays a crucial biological role in tumor formation. G4 is derived from DNA with good stability, and the DNA of serum samples is easy to obtain. Therefore, G4 has the potential… Show more
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