Predicting the threats of chemicals to wildlife: What are the challenges?

Hernout, Béatrice V.; Arnold, Kathryn E.; McClean, Colin J.; Grimm, Volker; Boxall, Alistair

doi:10.1002/ieam.198

Cited by 7 publications

(8 citation statements)

References 4 publications

(3 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A recent report, has indicated that since 1974 there has been a 60% decrease in wildlife populations worldwide (WWF, 2018). This alarming decrease responds to multiple causes, among which are the change in land uses, the destruction of the habitat of many species, the climate change, but also the penetration of chemistry in ecosystems (Hernout et al, 2011). A clear and very well documented example of the latter, is found in the drastic decline in populations of Asian vultures due to exposure to diclofenac, widely used as a veterinary antiinflammatory drug, and that in these birds, produces lethal nephropathy (Sathishkumar et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

Micro QuEChERS-based method for the simultaneous biomonitoring in whole blood of 360 toxicologically relevant pollutants for wildlife

Rial-Berriel

Acosta-Dacal

Zumbado

et al. 2020

Science of The Total Environment

View full text Add to dashboard Cite

• Validation of a method for the simultaneous quantification of 360 toxic chemicals in whole blood • One-step acetate buffered micro QuEChERS using acidified acetonitrile yielded recoveries N70%. • Only 250 μl of sample and quantification at the sub-ppb level makes it suitable for biomonitoring. • Verified in a series of 36 barn owls and 112 common kestrels, which test positive for 3-25 pollutants

show abstract

Section: Introductionmentioning

confidence: 99%

Micro QuEChERS-based method for the simultaneous biomonitoring in whole blood of 360 toxicologically relevant pollutants for wildlife

Rial-Berriel

Acosta-Dacal

Zumbado

et al. 2020

Science of The Total Environment

View full text Add to dashboard Cite

show abstract

“…It is important to highlight that our model outputs determine a risk based on the level of oral exposure while our tissue data considers internal exposure. The differences observed can be explained by a number of aspects of the modeling approach including the level of spatial and temporal resolution of the available metal soil concentration data, the effects of soil parameters on uptake into food items, the spatial availability of prey items and the bioavailability of metals from food items into the bats (Hernout et al, 2011(Hernout et al, , 2013. The sensitivity data (i.e.…”

Section: Discussionmentioning

confidence: 99%

Interspecies variation in the risks of metals to bats

Hernout

Pietravalle

Arnold

et al. 2015

Environmental Pollution

Self Cite

View full text Add to dashboard Cite

“…With little or no treatment of some manufacturing discharges or municipal and agricultural waste streams containing human and veterinary pharmaceuticals, risks to wildlife and humans are predicted to be high, but remain virtually unassessed [20,21]. Such scientific research could support future international development policies.…”

Section: Grand Challenges For Research Regulation and Policy Developmentioning

confidence: 99%

Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems

et al. 2013

Self Cite

View full text Add to dashboard Cite

The use of human and veterinary pharmaceuticals is increasing. Over the past decade, there has been a proliferation of research into potential environmental impacts of pharmaceuticals in the environment. A Royal Society-supported seminar brought together experts from diverse scientific fields to discuss the risks posed by pharmaceuticals to wildlife. Recent analytical advances have revealed that pharmaceuticals are entering habitats via water, sewage, manure and animal carcases, and dispersing through food chains. Pharmaceuticals are designed to alter physiology at low doses and so can be particularly potent contaminants. The near extinction of Asian vultures following exposure to diclofenac is the key example where exposure to a pharmaceutical caused a population-level impact on non-target wildlife. However, more subtle changes to behaviour and physiology are rarely studied and poorly understood. Grand challenges for the future include developing more realistic exposure assessments for wildlife, assessing the impacts of mixtures of pharmaceuticals in combination with other environmental stressors and estimating the risks from pharmaceutical manufacturing and usage in developing countries. We concluded that an integration of diverse approaches is required to predict ‘unexpected’ risks; specifically, ecologically relevant, often long-term and non-lethal, consequences of pharmaceuticals in the environment for wildlife and ecosystems.

show abstract

Predicting the threats of chemicals to wildlife: What are the challenges?

Cited by 7 publications

References 4 publications

Micro QuEChERS-based method for the simultaneous biomonitoring in whole blood of 360 toxicologically relevant pollutants for wildlife

Micro QuEChERS-based method for the simultaneous biomonitoring in whole blood of 360 toxicologically relevant pollutants for wildlife

Interspecies variation in the risks of metals to bats

Assessing the exposure risk and impacts of pharmaceuticals in the environment on individuals and ecosystems

Contact Info

Product

Resources

About