Predicting the Safe Use of Deceased After Circulatory Death Liver Allografts in Primary Sclerosing Cholangitis

Fleetwood, Vidya A.; Janek, Kevin C.; Leverson, Glen; Welch, Bridget; Yankol, Yücel; Foley, David P.; Mezrich, Josh; D’Alessandro, Anthony M.; Fernandez, Luis; Al‐Adra, David P.

doi:10.6002/ect.2020.0387

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Consensus: 80%1

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2023

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“…Extended criteria grafts, in particular those with high grade steatosis (i.e., >30% macro-steatosis) and grafts from older donors (i.e., >55 years old), represent risk factor for posttransplant complications, including recurrent biliary disease [33][34][35]. The use of livers donated after circulatory death (DCD) has also been associated with heightened risks of ischemic type biliary strictures [28,36].…”

Section: Consensus: 80%mentioning

confidence: 99%

Liver Transplantation for Primary Sclerosing Cholangitis (PSC) With or Without Inflammatory Bowel Disease (IBD)—A European Society of Organ Transplantation (ESOT) Consensus Statement

Carbone,

Della Penna,

Mazzarelli

et al. 2023

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Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of inflammatory bowel disease (IBD) and a lead indication for liver transplantation (LT) in the western world. In this article, we present a Consensus Statement on LT practice, developed by a dedicated Guidelines’ Taskforce of the European Society of Organ Transplantation (ESOT). The overarching goal is to provide practical guidance on commonly debated topics, including indications and timing of LT, management of bile duct stenosis in patients on the transplant waiting list, technical aspects of transplantation, immunosuppressive strategies post-transplant, timing and extension of intestinal resection and futility criteria for re-transplantation.

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