Predicting the prognosis in patients with sepsis by an endoplasmic reticulum stress gene signature
Jian Liu,
Hao Wang,
Huimin Xiao
et al.
Abstract:Background: Prognostic stratification of patients with sepsis is important for the development of individualized treatment strategies. Endoplasmic reticulum stress (ERS) plays a key role in sepsis. This study aimed to identify a set of genes related to ER stress to construct a predictive model for the prognosis of sepsis.
Methods: The transcriptomic and clinical data of 479 sepsis patients were obtained from GSE65682 and divided into a training set (n=288) and a validation set (n=191) at a ratio of … Show more
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