Predicting the need for massive transfusion in trauma patients

Ogura, Takayuki; Nakamura, Yoshihiko; Nakano, Minoru; Izawa, Yoshimitsu; Nakamura, Mitsunobu; Fujizuka, Kenji; Suzukawa, Masayuki; Lefor, Alan Kawarai

doi:10.1097/ta.0000000000000200

Cited by 80 publications

(76 citation statements)

References 35 publications

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“…The influence of hemorrhagic shock on the outcome of severely injured patients has been shown [16, 17]. Our data are consistent with these results, demonstrating significantly increased mortality, from 19.2% to 45.3% (p<0.001), in patients with clinically apparent shock on admission.…”

Section: Discussionsupporting

confidence: 92%

Association of an In-House Blood Bank with Therapy and Outcome in Severely Injured Patients: An Analysis of 18,573 Patients from the TraumaRegister DGU®

et al. 2016

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IntroductionHemorrhagic shock remains one of the most common causes of death in severely injured patients. It is unknown to what extent the presence of a blood bank in a trauma center influences therapy and outcome in such patients.Material and MethodsWe retrospectively analyzed prospectively recorded data from the TraumaRegister DGU® and the TraumaNetzwerk DGU®. Inclusion criteria were Injury Severity Score (ISS) ≥ 16, primarily treated patients, and hospital admission 2 years before or after the audit process.ResultsComplete data sets of 18,573 patients were analyzed. Of 457 hospitals included, 33.3% had an in-house blood bank. In trauma centers with a blood bank (HospBB), packed red blood cells (PRBCs) (21.0% vs. 17.4%, p < 0.001) and fresh frozen plasma (FFP) (13.9% vs. 10.2%, p <0.001) were transfused significantly more often than in hospitals without a blood bank (Hosp0). However, no significant difference was found for in-hospital mortality (standard mortality ratio [SMR, 0.907 vs. 0.945; p = 0.25). In patients with clinically apparent shock on admission, no difference of performed transfusions were present between HospBB and Hosp0 (PRBCs, 51.4% vs. 50.4%, p = 0.67; FFP, 32.7% vs. 32.7%, p = 0.99), and no difference in in-hospital mortality was observed (SMR, 0.907 vs. 1.004; p = 0.21).DiscussionIn HospBB transfusions were performed more frequently in severely injured patients without positively affecting the 24h mortality or in-house mortality. Easy access may explain a more liberal transfusion concept.

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Section: Discussionsupporting

confidence: 92%

Association of an In-House Blood Bank with Therapy and Outcome in Severely Injured Patients: An Analysis of 18,573 Patients from the TraumaRegister DGU®

et al. 2016

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“…The predictive value of the TBSS for MT was then validated using data from 113 severely injured trauma patients. The TBSS is defined as the sum of the component scores and ranges from 0 to 57 points (6). The sensitivity and specificity for a TBSS greater than 15 points were 97.4% and 96.2%, respectively.…”

Section: The Traumatic Bleeding Severity Scorementioning

confidence: 99%

Early Prediction of Ongoing Hemorrhage in Severe Trauma: Presentation of the Existing Scoring Systems

Tonglet

2016

Arch Trauma Res

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Early prediction of ongoing hemorrhage may reduce mortality via the earlier delivery of blood products, adequate orientation of the patient in a dedicated highly specialized and trained infrastructure, and by earlier correction of acute traumatic coagulopathy. We identified 14 scores or algorithms developed for the prediction of ongoing hemorrhage and the need for massive transfusion in severe trauma patients.

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“…However, given that current recommendations are based on preoperative serum haemoglobin level or the identification of symptoms of anaemia, the guidelines may be limited as they do not account for other perioperative risk factors including procedure type, presence of preoperative bleeding disorders and pre‐existing co‐morbidity. To account for these varying patient characteristics associated with the receipt of transfusion, several scoring systems and nomograms have been proposed to predict blood transfusion requirements following cardiac and spinal surgery, as well as major trauma. The present study aimed to define demographic and preoperative risk factors associated with blood transfusion among patients undergoing major hepatopancreaticobiliary (HPB) and colorectal surgery at a large tertiary‐care centre.…”

Section: Introductionmentioning

confidence: 99%

Nomogram to predict perioperative blood transfusion for hepatopancreaticobiliary and colorectal surgery

Kim

Bagante

Gani

et al. 2016

British Journal of Surgery

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Predicting the need for massive transfusion in trauma patients

Abstract: Prognostic study, level III.

Cited by 80 publications

References 35 publications

Association of an In-House Blood Bank with Therapy and Outcome in Severely Injured Patients: An Analysis of 18,573 Patients from the TraumaRegister DGU®

Association of an In-House Blood Bank with Therapy and Outcome in Severely Injured Patients: An Analysis of 18,573 Patients from the TraumaRegister DGU®

Early Prediction of Ongoing Hemorrhage in Severe Trauma: Presentation of the Existing Scoring Systems

Nomogram to predict perioperative blood transfusion for hepatopancreaticobiliary and colorectal surgery

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