Predicting the Effect of miRNA on Gene Regulation to Foster Translational Multiomics Research – A Thorough Review on the Role of ChIP-Seq Data
Sarmistha Das,
Shesh N Rai
Abstract:Gene regulation is vital for cellular function and homeostasis, involving diverse mechanisms controlling specific gene products and contributing to tissue-specific gene expression. Dysregulation leads to diseases, emphasizing the need for understanding these mechanisms. Non-coding regions, notably enhancers and super-enhancers (SEs), act as crucial gene regulators, orchestrating transcriptional activity via transcription factors (TFs). SEs, with high activity, are pivotal in cell identity and disease progressi… Show more
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