Predicting Swallowing Outcomes from Objective Videofluoroscopic Timing and Displacement Measures in Head and Neck Cancer Patients

Vansant, Mathew B.; Parker, Lindsey A.; McWhorter, Andrew J.; Bluoin, David

doi:10.1007/s00455-020-10091-5

Cited by 5 publications

(2 citation statements)

References 30 publications

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“…The current findings would be useful as reference for VFSS findings in NPC survivors, but should not be used alone as diagnostic criteria for dysfunction. While kinematic measures of swallowing can be reflective of functional swallowing outcomes in head and neck cancers [48], they would be best advised to be used in conjunction with validated and standardised swallowing assessment methods.…”

Section: Limitationsmentioning

confidence: 99%

The Relationships Between Radiation Dosage and Long-term Swallowing Kinematics and Timing in Nasopharyngeal Carcinoma Survivors

Lee

Chan

et al. 2021

Dysphagia

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This study aimed to investigate the relationship between intensity-modulated radiation therapy (IMRT) dosimetry and swallowing kinematic and timing measures. Thirteen kinematic and timing measures of swallowing from videofluoroscopic analysis were used as outcome measures to reflect swallowing function. IMRT dosimetry was accessed for thirteen swallowing-related structures. A cohort of 44 nasopharyngeal carcinoma (NPC) survivors at least 3 years post-IMRT were recruited. The cohort had a mean age of 53.2 ± 11.9 years, 77.3% of whom were male. There was an average of 68.24 ± 14.15 months since end of IMRT; 41 (93.2%) had undergone concurrent chemotherapy. For displacement measures, female sex and higher doses to the cricopharyngeus, glottic larynx, and base of tongue were associated with reduced hyolaryngeal excursion and pharyngeal constriction, and more residue. For timing measures, higher dose to the genioglossus was associated with reduced processing time at all stages of the swallow. The inferior pharyngeal constrictor emerged with a distinctly different pattern of association with mean radiation dosage compared to other structures. Greater changes to swallowing kinematics and timing were observed for pudding thick consistency than thin liquid. Increasing radiation dosage to swallowing-related structures is associated with reduced swallowing kinematics. However, not all structures are affected the same way, therefore organ sparing during treatment planning for IMRT needs to consider function rather than focusing on select muscles. Dose-response relationships should be investigated with a comprehensive set of swallowing structures to capture the holistic process of swallowing.

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Section: Limitationsmentioning

confidence: 99%

The Relationships Between Radiation Dosage and Long-term Swallowing Kinematics and Timing in Nasopharyngeal Carcinoma Survivors

Lee

Chan

et al. 2021

Dysphagia

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“…Several anatomical landmarks have been used as UES proxies, but not consistently between studies. Landmarks include the trachea (15-20 mm below the top of the tracheal air column 5 ), vocal folds (10-20 mm inferior to the vocal folds [6][7][8][9] ), and the cervical vertebrae (the narrowest region between C3 and C6 [10][11][12][13][14][15] or C4-C6 [16][17][18][19][20] ).…”

Section: Introductionmentioning

confidence: 99%

Location of the upper oesophageal sphincter during swallowing: Analysis using swallowing CT

Gao,

Inamoto,

Saitoh

et al. 2024

J of Oral Rehabilitation

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BackgroundUpper oesophageal sphincter (UES) serves as an important anatomical and functional landmark during swallowing. However, the precise UES location before and during swallowing has not been well established.ObjectiveThis study aimed to determine upper oesophageal sphincter (UES) location and displacement during swallowing accounting for sex, age, and height in healthy adults using 320‐row area detector computed tomography (320‐ADCT).MethodsNinety‐four healthy adults (43 males; 22–90 years) underwent 320‐ADCT scanning while swallowing one trial of 10 mL honey thick barium. UES location at bolus hold and at maximum displacement and vertical displacement during swallowing were identified using the coordinates and the section classification of vertebrae (VERT scale). The differences and correlations of UES location and distance in terms of sex, age, and height were analysed using Mann–Whitney U test and Spearman's correlation coefficient.ResultsUES locations at bolus hold and at maximum displacement were significantly lower and UES vertical displacement was significantly larger in males than in females (p < .001). UES location at bolus hold became lower with increasing age (r = −.312, p = .002), but the negative correlation was low at maximum displacement (r = −.230, p = .026), resulting in larger vertical distance with ageing. UES locations showed high negative correlation at bolus hold with height (r = −.715, p < .001), and showed moderate negative correlation at maximum displacement with height (r = −.555, p < .001), although this effect was unclear when analysed by sex.ConclusionMales showed lower UES location and larger displacement than females. The impact of age was evident with lower location before swallowing and larger displacement during swallowing. Differences observed by sex were not completely explained by using the VERT scale to adjust for height.

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Efficient Patient Orientation Detection in Videofluoroscopy Swallowing Studies

et al. 2022

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Predicting Swallowing Outcomes from Objective Videofluoroscopic Timing and Displacement Measures in Head and Neck Cancer Patients

Cited by 5 publications

References 30 publications

The Relationships Between Radiation Dosage and Long-term Swallowing Kinematics and Timing in Nasopharyngeal Carcinoma Survivors

The Relationships Between Radiation Dosage and Long-term Swallowing Kinematics and Timing in Nasopharyngeal Carcinoma Survivors

Location of the upper oesophageal sphincter during swallowing: Analysis using swallowing CT

Efficient Patient Orientation Detection in Videofluoroscopy Swallowing Studies

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