Predicting survival in out-of-hospital cardiac arrest patients undergoing targeted temperature management: The Polish Hypothermia Registry Risk Score

Abstract

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Artificial neural network-boosted Cardiac Arrest Survival Post-Resuscitation In-hospital (CASPRI) score accurately predicts outcome in cardiac arrest patients treated with targeted temperature management

“…One such model, the Acute Physiology and Chronic Health Evaluation (APACHE) II score for predicting favorable neurological outcome for patients with OHCA who received TTM exhibited an acceptable discrimination power with an AUC of 0.697 27 . Another model called the Mild Therapeutic Hypothermia score for predicting in-hospital mortality among OHCA patients treated with TTM, reported an AUC of 0.74 28 , while the risk score proposed by Martinell et al for patients with OHCA receiving TTM yielded AUCs of 0.818–0.842 16 . These scoring systems only demonstrated moderate accuracy, thus, limiting their clinical applications for precise outcome prediction or patient stratification.…”

Out-of-hospital cardiac arrest: A systematic review of current risk scores to predict survival

“…All the 11 scoring systems predicting mortality included in this review were developed specifically for this purpose (11)(12)(13)(14)(15)(16)(17)(18)(19)(20) except the OHCA score (21), which was initially developed to assess neurological function on discharge but has been used in validation cohorts to assess mortality outcome.…”

“…The recently published PHR-RS, (19) was developed from the data of 376 patients who received TTM, to identify characteristics which were predictive of death; namely age and components of the mild therapeutic hypothermia score which mainly comprises of arrest characteristics. The score showed an AUC of 0.74 for predicting in-hospital death, but is complicated to calculate and has not been externally validated.…”

Does ticagrelor effectively inhibit platelets in patients undergoing mild therapeutic hypothermia or it does not?

“…Out-of-hospital cardiac arrest (OHCA) is a common complication of acute myocardial infarction (MI) [1][2][3][4][5][6][7][8][9]. The results of studies on the impact of mild therapeutic hypothermia (MTH) in OHCA survivors are inconclusive [10][11][12][13][14].…”