“…Among the 18 studies that did not use validated de-pression instruments, 10 were cross-sectional studies, and all of these studies found the statistically significant relationship between smoking and depression (Boys et al, 2003;Brooks et al, 2002;Coogan et al, 1998;Covey & Tam, 1990;Landrine et al, 1994;LloydRichardson et al, 2002;Martini et al, 2002;Otsuki, 2003;Pesa, Cowdery, Wang, & Fu, 1993;Wang et al, 1994). Five of eight longitudinal studies found the statistically significant relationships between smoking and depression: Three studies found depression as an antecedent to smoking, and two studies found the bidirectional relationship between smoking and depression (Dierker et al, 2004;Fleming et al, 2002;Gilpin et al, 2004;Goodman & Captman, 2000;Wang et al, 1996).…”