Predicting prognosis outcomes of primary central nervous system lymphoma with high-dose methotrexate-based chemotherapeutic treatment using lipidomics
Yi Zhong,
Liying Zhou,
Jingshen Xu
et al.
Abstract:Background
Primary central nervous system lymphoma (PCNSL) is a rare extranodal lymphomatous malignancy which is commonly treated with high-dose methotrexate (HD-MTX)-based chemotherapy. However, the prognosis outcome of HD-MTX-based treatment cannot be accurately predicted using the current prognostic scoring systems, such as the Memorial Sloan Kettering Cancer Center (MSKCC) score.
Methods
We studied two cohorts of patients… Show more
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