2009
DOI: 10.1186/1471-2407-9-389
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Predicting prognosis in hepatocellular carcinoma after curative surgery with common clinicopathologic parameters

Abstract: BackgroundSurgical resection is one important curative treatment for hepatocellular carcinoma (HCC), but the prognosis following surgery differs substantially and such large variation is mainly unexplained. A review of the literature yields a number of clinicopathologic parameters associated with HCC prognosis. However, the results are not consistent due to lack of systemic approach to establish a prediction model incorporating all these parameters.MethodsWe conducted a retrospective analysis on the common cli… Show more

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Cited by 111 publications
(111 citation statements)
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“…HCC associates a dismal prognosis because of late presentation of the disease and high risk of postoperative tumour recurrence (Hao et al, 2009). Although the risk factors for HCC are well known (Kemp et al, 2005), the cellular and molecular mechanisms contributing to hepatocarcinogenesis are poorly understood.…”
Section: Introductionmentioning
confidence: 99%
“…HCC associates a dismal prognosis because of late presentation of the disease and high risk of postoperative tumour recurrence (Hao et al, 2009). Although the risk factors for HCC are well known (Kemp et al, 2005), the cellular and molecular mechanisms contributing to hepatocarcinogenesis are poorly understood.…”
Section: Introductionmentioning
confidence: 99%
“…20 The clinical-pathological correlation of HCC patients was analyzed by SPSS for Windows 16.0 (SPSS, Chicago, IL). Categorical data were analyzed via Fisher's exact test, whereas an independent t test was used for continuous data.…”
Section: Patient Samples and Statistical Analysesmentioning
confidence: 99%
“…In China, the mortality rate of HCC is the second highest of all cancers, and the five-year survival rate is less than 5% with nearly 60,000 HCC patients succumbing to the disease every year (2). Increasing evidence suggests that multiple genetic and epigenetic alterations contribute to the tumorigenesis of different cancers.…”
Section: Introductionmentioning
confidence: 99%