Predicting posterior capsule opacification: Value of early retroillumination imaging

Abstract

Retroillumination imaging of the posterior capsule 6 months after cataract surgery predicted the PCO outcome at 2 years in eyes with foldable IOLs.

Comparison of posterior capsule opacification rates between hydrophilic and hydrophobic single-piece acrylic intraocular lenses

“…There was no significant difference in visual performance between the 2 IOLs at 1 year, but based on prediction of PCO development, it is likely that eyes with hydrophilic IOLs will develop visually significant changes from PCO with time. 27 Eyes with the hydrophobic IOL had less PCO over time. Regression of LECs on the posterior capsule in eyes with hydrophobic IOLs has been reported.…”

Biomaterial Influence on Intraocular Lens Performance: An Overview

“…After 3 years of follow-up, they found significantly less PCO and lower Nd:YAG laser capsulotomy rates in the eyes implanted with the hydrophobic IOL than in the plate-haptic silicone IOL group. Other studies [ 12 , 21 , 39 , 43 , 45 ] also compared PCO and Nd:YAG rates resulting from 3-piece, round optic-edge silicone IOL (SI30N/SI40NB, AMO) and 3-piece, sharp-edge hydrophobic acrylic IOL (AcrySof, Alcon) implantation. Most of these studies revealed that following phacoemulsification, PCO rates increased over the years for all groups and that the benefit yielded by the acrylic IOL in terms of showing lower PCO rates faded as the years went by: after a long follow-up period, up to 12 years of follow-up, the PCO and Nd:YAG treatment rates were similar for both groups.…”

In vivo digital imaging of the square-edged barrier effect of a silicone intraocular lens

“…Systematic attempts at tracking early PCO development in vivo are rare. 12,[19][20][21][22]24 In a recent example, Bender et al 19 examined retroillumination photographs 6 months and 2 years after uneventful phacoemulsification and implantation of different types and models of IOLs. They found that the correlation coefficient between the percentage of PCO at 6 months and at 2 years was 0.71 overall.…”

“…13 Determining whether a specific IOL leads to a higher or lower PCO rate than another IOL has generally been accomplished through 1 of 3 methods: monitoring groups of patients in whom specific IOLs are implanted [14][15][16][17] ; tracking PCO or Nd:YAG capsulotomies visible in posterior photographs of eye-bank eyes 1,9,18 ; quantifying the late PCO visible in retroillumination photographs of patients' eyes. 12,14,[19][20][21][22] These methods rely on IOLs that have been in wide use 2 to 3 years before the incidence of PCO can be stated reliably.…”