Predicting Pathologic Bone Lesions Using Scout Computed Tomography (CT) Imaging

Abstract

The purpose of this study is to evaluate the benefit of reviewing scout CT images, obtained for routine oncologic surveillance, for the early identification of pathologic bony lesions. A retrospective review was conducted on patients who previously underwent surgical treatment by two orthopedic oncology surgeons at a tertiary care institution from 2009–2019 for pathologic lesions or fractures of the humerus or femur. Radiographic records were reviewed to identify patients in this cohort who had available scout views from CT imaging prior to official diagnosis of the bony lesion or fracture. CT scout images were assessed by two independent reviewers to identify any pathologic lesions, and radiographic reports were reviewed to identify if the lesions were noted by radiology at the time of the initial scan interpretation. One hundred and forty-four patients were identified, and thirty-nine had an available scout CT image prior to official diagnosis of the lesion. Twenty-five patients (64.1%) had lesions identified by authors on scout CT versus only 9 (23.1%) who had lesions that were documented in the initial CT radiologic report. There was a total of 29 lesions identified by the study authors on scout CT, and 19 (65.5%) were not reported in the initial radiographic interpretation with an average interval between observation by authors and official diagnosis of 202 days. Of the impending fractures, three patients (16.7%) went on to complete fracture prior to referral to orthopedics with an average interval between these missed lesions on scout CT and their presentation with fracture of 68 days. This study advocates for the careful review of all scout CT imaging as an essential part of the work up for metastatic disease and encourages all practitioners to utilize this screening tool for the identification of pathologic bony lesions which may help expedite early treatment to reduce patient morbidity.

Current concepts in metastatic carcinoma: a review of the literature

“…In previous studies, CT was able to identify a primary site of malignancy in 88% of patients who presented with metastases of unknown origin. [8][9][10] Colello et al 11 demonstrated the importance of review of a Scout CT imaging review as a means to further identify potential metastatic lesions in the surrounding appendicular skeleton. 11 Additionally, a bone scan should be performed to assess the entire skeleton.…”

“…[8][9][10] Colello et al 11 demonstrated the importance of review of a Scout CT imaging review as a means to further identify potential metastatic lesions in the surrounding appendicular skeleton. 11 Additionally, a bone scan should be performed to assess the entire skeleton. Bone scintigraphy makes use of technetium (Tc-99m) as the active agent and detects osteoblastic activity (Figure 3).…”

“…Colello et al 11. demonstrated the importance of review of a Scout CT imaging review as a means to further identify potential metastatic lesions in the surrounding appendicular skeleton 11…”