Predicting Mortality 12 Years After an Acute Cardiac Event

Murphy, Barbara; Rogerson, Michelle; Worcester, Marian U.C.; Elliott, Peter; Higgins, Rosemary; Grande, Michael Le; Turner, Alyna; Goble, Alan J.

doi:10.1097/hcr.0b013e318283927f

Cited by 22 publications

(12 citation statements)

References 33 publications

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“…The negative health impacts appear to surface or increase when anxiety or depressive symptoms persist or emerge after hospital discharge during convalescence (Blumenthal et al, 2003;Murphy et al, 2013;Worcester et al, 2019;Kim et al, 2020). In a 12-year follow-up study of 170 female AMI and CABGS patients, we found that the mortality rate was highest in those whose depression symptoms worsened in the 2 months after hospital discharge, and lowest in those whose inhospital symptoms remitted by 2 months (Murphy et al, 2013). Others have reported similar findings (Blumenthal et al, 2003).…”

Section: Introductionsupporting

confidence: 63%

“…It is generally agreed that around one in five patients meet diagnostic criteria for depression while hospitalized for a cardiac event (Thombs et al, 2006;Lichtman et al, 2008;Colquhoun et al, 2013;Murphy et al, 2016), and up to one in three experience severe anxiety (Andrew et al, 2000;Tully and Baker, 2012;Murphy et al, 2016). While relatively few studies have reported rates of anxiety and depression at later points during patients' convalescence, there is evidence that early symptoms resolve for many patients during the first few months after hospital discharge (Murphy et al, 2008a(Murphy et al, , 2013(Murphy et al, , 2016.…”

Section: Introductionmentioning

confidence: 99%

“…Patients who are anxious or depressed after an acute cardiac event are at increased risk of a subsequent event and premature death (Strik et al, 2003;Barth et al, 2004;van Melle et al, 2004;Tully et al, 2013). The negative health impacts appear to surface or increase when anxiety or depressive symptoms persist or emerge after hospital discharge during convalescence (Blumenthal et al, 2003;Murphy et al, 2013;Worcester et al, 2019;Kim et al, 2020). In a 12-year follow-up study of 170 female AMI and CABGS patients, we found that the mortality rate was highest in those whose depression symptoms worsened in the 2 months after hospital discharge, and lowest in those whose inhospital symptoms remitted by 2 months (Murphy et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

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Anxiety and Depression After a Cardiac Event: Prevalence and Predictors

et al. 2020

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Introduction: Patients who are anxious or depressed after an acute cardiac event are at increased risk of a subsequent event and premature death. It is therefore important to identify these patients early in order to initiate supportive or even preventive measures. In the present study, we report on the prevalence of anxiety and depression during the first 12 months after an acute cardiac event, and the patient characteristics predictive of increased anxiety and depression risk in early and late convalescence. Methods: We recruited a sample of 911 patients with acute myocardial infarction (AMI), acute coronary syndrome (ACS), and/or unstable angina (UA), and/or undergoing coronary artery bypass graft surgery (CABGS). Patients completed the Hospital Anxiety and Depression Scale (HADS) close to the time of their event, and again during early (2-4 months post-event) and late (6-12 months post-event) convalescence. Using HADS-A and HADS-D cutoffs of 8+, prevalence rates for anxiety, depression, and comorbid anxiety and depression were determined for each timepoint. Chi-square tests and odds ratios were used to identify baseline patient characteristics associated with increased anxiety and depression risk over 12 months. Results: Anxiety rates were 43, 28, and 27% at the time of the event, early, and late convalescence. Depression rates were 22, 17, and 15%, respectively. Factors consistently associated with increased anxiety and depression risk were history of depression, financial strain, poor self-rated health, low socioeconomic status, younger age (<55 years), and smoking. Obesity, diabetes, and social isolation (living alone or being unpartnered) were identified as important albeit less significant risk factors. Neither sex nor event type were predictive of anxiety or depression. Conclusion: This large patient sample provided the opportunity to identify rates of anxiety and depression during the 12 months after a cardiac event and key patient characteristics for increased risk. These risk factors are easily identifiable at the time of the event, and could be used to guide the targeting of support programs for patients at risk.

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Section: Introductionsupporting

confidence: 63%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Anxiety and Depression After a Cardiac Event: Prevalence and Predictors

et al. 2020

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“…Normal levels of pre-CABG depression are observed, although other studies have indicated higher levels, from moderate to severe [92]. However, more than 25% of patients with normal levels are at risk of worsening, for which reason continuous reassessment can identify patients with transient symptoms of depression [93].…”

Section: Discussionmentioning

confidence: 97%

“…Some authors report that more than 50% of patients were receiving medical treatment for depression, even though they had no symptoms of depression [106]. For this reason, the use of measurement tools to confirm the presence and levels of depression makes it possible to identify the at-risk patients, and therefore carry out a more in-depth post-CABG follow-up, of at least nine months [93].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Depression in Coronary Artery Bypass Surgery: A Systematic Review and Meta-Analysis

Correa‐Rodríguez

Ejheisheh

Suleiman‐Martos

et al. 2020

JCM

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Coronary artery bypass graft surgery (CABG) might adversely affect the health status of the patients, producing cognitive deterioration, with depression being the most common symptom. The aim of this study is to analyse the prevalence of depression in patients before and after coronary artery bypass surgery. A systematic review and meta-analysis was carried out, involving a study of the past 10 years of the following databases: CINAHL, LILACS, MEDLINE, PsycINFO, SciELO, Scopus, and Web of Science. The total sample comprised n = 16,501 patients. The total number of items was n = 65, with n = 29 included in the meta-analysis. Based on the different measurement tools used, the prevalence of depression pre-CABG ranges from 19–37%, and post-CABG from 15–33%. There is a considerable presence of depression in this type of patient, but this varies according to the measurement tool used and the quality of the study. Systematically detecting depression prior to cardiac surgery could identify patients at potential risk.

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Scared for the scar: fearsome impact of acute cardiovascular disease on perceived kinesiophobia (fear of movement)

Brunetti

Guerra

Ieva

et al. 2017

Clinical Cardiology

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Background To assess levels of kinesiophobia (fear of movement) in patients hospitalized for acute cardiovascular disease. Hypothesis Increased levels of kinesiophobia can be found in subjects hospitalized for acute cardiovascular disease. Methods Seventy‐four consecutive patients admitted for acute coronary syndrome and 58 for acute heart failure were enrolled in the study and assessed by the Tampa Scale for the evaluation of kinesiophobia. Subjects were compared with a reference population with stable coronary artery disease and healthy controls. Results No significant differences were found between acute coronary syndrome and acute heart failure in terms of kinesiophobia, even considering the rates of high kinesiophobia (Tampa score >37) and the 4 groups of questionnaire items (danger, fear, avoidance, dysfunction). Differences, however, were significant comparing our population with an historical population of subjects with stable coronary artery disease and controls (43 ± 5 vs 35 ± 7 vs 33 ± 6, P < 0.0001 in both cases). A significant correlation was found between the grade of kinesiophobia in the Tampa Scale and the age of subjects (r = 0.27, P = 0.001) and inversely with level of education (r = −0.33, P < 0.0001). Conclusions Increased levels of kinesiophobia can be found in subjects hospitalized for acute cardiovascular disease. Kinesiophobia is related to age and education. Kinesiophobia should be carefully considered in subjects hospitalized in acute cardiac care units.

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Predicting Mortality 12 Years After an Acute Cardiac Event

Abstract: Mild inhospital depression and moderate/severe 2-month depression were predictive of 12-year deaths. The findings suggest a prognostic benefit in undertaking repeat depression screening 2 months after an acute cardiac event.

Cited by 22 publications

References 33 publications

Anxiety and Depression After a Cardiac Event: Prevalence and Predictors

Anxiety and Depression After a Cardiac Event: Prevalence and Predictors

Prevalence of Depression in Coronary Artery Bypass Surgery: A Systematic Review and Meta-Analysis

Scared for the scar: fearsome impact of acute cardiovascular disease on perceived kinesiophobia (fear of movement)

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