Predicting Lactate Elevation in Neonatal Cardiac Surgery: Can the Sugars be Overlooked?

Abstract

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Predicting Kidney Injury Following Valvular Heart Surgery in An Elderly Cohort: The Missing Links…

“…While preoperative diabetes mellitus did not emerge as a baseline risk-predictor of CS-AKI (19.7% and 15.6% incidence in AKI and non-AKI population, respectively), the lack of elucidation of perioperative glucose homeostasis in the present study captivates attention, particularly when poor glucose control has been linked to an enhanced propensity for CS-AKI owing to an augmented oxidative stress, endothelial dysfunction and systemic inflammatory response [ 2 - 4 ] . Moreover, the authors also fail to delineate their institutional perioperative glucose management protocol.…”

COVID-19 Positive Cohort Undergoing Cardiac Surgery: A Possible Un(3H)oly Trinity of HypoxiaHemolysis-Hyperinflammation

“…Moreover, CPB-related hemodilution makes the matter even worse. Whileprolonged aortic cross-clamp and CPB times translate into ischemic tissue burden, the concerns about circulatory arrest (mandatory for complex open-heart surgeries) become manifold [ 5 , 6 ] .…”

Liver transplant and the sweet-bitter truth

“…Indeed, the total ischemia time in the hyperlactatemia group was higher in the analysis by Kim et al [ 1 ]. Apart from ischemia, prior studies have also associated hyperglycemia with concomitant lactate elevations in diverse clinical settings, indicating glycometabolic interactions [ 5 ].…”

“…Irrespective of whether it is viewed as an independent prognosis or as glycometabolic interactions [ 5 ], hyperglycemia in LT cannot be neglected.…”