Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics
Vaishali P. Waman,
Paul Ashford,
Su Datt Lam
et al.
Abstract:The COVID-19 disease is an ongoing global health concern. Although vaccination provides some protection, people are still susceptible to re-infection. Ostensibly, certain populations or clinical groups may be more vulnerable. Factors causing these differences are unclear and whilst socioeconomic and cultural differences are likely to be important, human genetic factors could influence susceptibility. Experimental studies indicate SARS-CoV-2 uses innate immune suppression as a strategy to speed-up entry and rep… Show more
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