Predicting Differential Renal Function Using Computerized Tomography Measurements of Renal Parenchymal Area

Feder, Marc; Blitstein, Jeffery; Mason, Barry M.; Hoenig, David M.

doi:10.1016/j.juro.2008.07.057

Cited by 25 publications

(23 citation statements)

References 3 publications

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“…In addition, the parenchymal thickness of the punctured calyx-posterior lower pole was used as a parameter in the present study. The lack of correlation between RPT and eGFR might be related to this reason in this study [17]. However, despite these limitations, considering the lack of any study evaluating the effect of RP thickness on the outcomes of PNL, this study is a valuable contribution to the existing data.…”

Section: Discussionmentioning

confidence: 92%

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Parenchymal Thickness: Does It Have an Impact on Outcomes of Percutaneous Nephrolithotomy?

et al. 2013

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Objective: To evaluate whether renal parenchymal thickness (RPT) has an effect on the outcomes of percutaneous nephrolithotomy (PNL). Methods: We performed a retrospective analysis of 144 patients with lower pole and/or renal pelvic stones who underwent PNL. The relationship between RPT and peri- and postoperative measures was evaluated. Results: The average age was 45.94 ± 14.47 (15-76) years. The mean BMI was calculated as 27.47 ± 4.73 (16.9-44.9) kg/m². The mean stone burden was 293 ± 126 (150-800 mm²). The mean RPT was measured as 17.33 ± 5.32 (6-35) mm. No correlation was detected between the RPT and the operation or fluoroscopy times or the duration of hospitalization (p = 0.63, 0.52, 0.08, respectively). The mean drop in hemoglobin level was 1.45 ± 1.25 (0-9) g/dl. A negative correlation was detected between hemoglobin drop and RPT (p = 0.01, r = -0.23). However, the RPT was similar in patients who did or did not require a blood transfusion (p = 0.09). The RPT was found to have no impact on success rate (p = 0.4). Conclusion: The postoperative hemoglobin drop increases in parallel with the increase in RPT. However, no relationship was detected between the RPT and blood transfusion, overall success rate or any other perioperative parameters.

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Section: Discussionmentioning

confidence: 92%

“…The RPT is accepted as an indicator of relative renal function in chronic obstructive renal disease and an independent variable to predict the recoverability of renal function after resolution of the obstruction [13,14,15,16,17]. The size and thickness of the kidney are affected by various congenital and acquired conditions and age.…”

Section: Discussionmentioning

confidence: 99%

Parenchymal Thickness: Does It Have an Impact on Outcomes of Percutaneous Nephrolithotomy?

et al. 2013

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“…The correlation between the renal parenchymal area on computed tomography and function has been previously established. 13 Computed volumetry was also proposed as a surrogate for function in the kidney donor population for unobstructed renal units. 14,15 Sarma et al recently reported a strong correlation between percent renal volume and percent renal function in obstructed units (r = 0.828, p < 0.001) as well as in nonobstructed units (r = 0.827, p < 0.001).…”

Section: Discussionmentioning

confidence: 99%

Three-Dimensional Renal Parenchymal Volume as a Surrogate for Renal Function Estimation in Obstructed Kidneys Undergoing Surgical Repair

Martinez-SuarezHumberto

DursoTimothy

KadlecAdam

et al. 2015

Journal of Endourology

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There is a significant correlation between percent total RPV determined by 3D reconstruction of CT scan images and SDF as determined by diuretic renography in obstructed kidneys. CT-based percent RPV has potential as a functional assessment tool in obstructed kidneys. With further validation, it may be used to counsel patients considering surgical repair of ureteral or ureteropelvic junction obstruction.

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“…Feder et al suggested that renal parenchymal areas measured by CT strongly correlate with the results of the renal scans [15]. The overall averaged difference in calculating differential function by CT versus that of renal scan was only 4.73% [15]. According to these results, measurement of DRF in kidneys with a significant size difference could be riddled with pitfalls.…”

Section: Discussionmentioning

confidence: 99%

Modified Differential Renal Function Measurement Revised by Renal Cross Sectional Area in Children with Ureteropelvic Junction Obstruction

Nam

Chung

2010

Korean J Urol

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PurposeDiuretic 99mTc-diethylenetriaminepentaacetic acid (Tc-DTPA) renal scans may show false-negative or false-positive results in children with ureteropelvic junction obstruction (UPJO). We evaluated whether modified differential renal function (DRF) revised by the renal cross-sectional area on imaging study may be a more valuable predictor than conventional DRF on a renal scan for deciding on a proper interventional time.Materials and MethodsBetween September 2001 and January 2008, we reviewed the diuretic renal scan results of 29 pediatric patients who underwent pyeloplasty due to unilateral UPJO. Diuretic renal scans using the standard 99mTc-DTPA protocol and imaging studies for renal unit measurement area were done. Conventional DRF measurement and modified calculation of DRF per unit area were done. Conventional DRF was classified into group I (below 40%) and group II (above 40%).ResultsThe mean age of all patients was 42.6±52.6 months (range, 3-198 months). The mean cross-sectional areas of the UPJO kidney and of the normal contralateral kidney were 62.1±29.2 cm2 and 41.3±22.5 cm2, respectively (p<0.01). The conventional and modified DRF of the UPJO kidney were 45.2±9.2% and 35.2±9.5%, respectively (p<0.01). Thirteen children (62%) in group II (n=21) were classified in group I by the modified DRF measurement.ConclusionsThe modified DRF measurement calculated according to cross-sectional area showed fewer false-negative results and may be a valuable method for deciding on pyeloplasty under equivocal circumstances.

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Predicting Differential Renal Function Using Computerized Tomography Measurements of Renal Parenchymal Area

Abstract: Differential renal parenchymal area measured by computerized tomography strongly correlates with differential function on renal scintigraphy and it may obviate the need for nuclear renal scan in some circumstances.

Cited by 25 publications

References 3 publications

Parenchymal Thickness: Does It Have an Impact on Outcomes of Percutaneous Nephrolithotomy?

Parenchymal Thickness: Does It Have an Impact on Outcomes of Percutaneous Nephrolithotomy?

Three-Dimensional Renal Parenchymal Volume as a Surrogate for Renal Function Estimation in Obstructed Kidneys Undergoing Surgical Repair

Modified Differential Renal Function Measurement Revised by Renal Cross Sectional Area in Children with Ureteropelvic Junction Obstruction

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