Predicted normal values of pulmonary function tests in normal Korean children

Park, Chul Hyue; Kim, Hyo Bin; Jung, Young Ho; Lee, Eun; Yang, Song I; Seo, Ju Hee; Kwon, Ji‐Won; Kim, Hyung Young; Kim, Byoung Ju; Lee, So Yeon; Song, Dae Jin; Jang, Gwang Cheon; Kim, Woo Kyung; Shim, Jung Yeon; Hong, Soo Jong

doi:10.4168/aard.2014.2.3.187

Cited by 11 publications

(6 citation statements)

References 15 publications

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“…No difference was found between boys and girls. Height, area of body surface, and weight correlate with pulmonary function in descending order 27 ) , a result which is consistent with the results of our present study. Girls showed higher correlation than boys between percent body fat and pulmonary function in the present study.…”

Section: Discussionsupporting

confidence: 93%

Correlation between basic physical fitness and pulmonary function in Korean children and adolescents: a cross-sectional survey

et al. 2015

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[Purpose] The purpose of the present study was to determine whether there was a correlation between basic physical fitness and pulmonary function in Korean school students, to present an alternative method for improving their pulmonary function. [Subjects and Methods] Two hundred forty healthy students aged 6–17 years performed physical fitness tests of hand-grip strength, sit and reach, Sargent jump, single leg stance, and pulmonary function tests of forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) using a Quark PFT. [Results] Muscle strength and power of boys improved in the late period of elementary school and middle school. Muscle strength of girls improved in the late period of elementary school. Analysis of factors affecting pulmonary function revealed that height, weight, BMI, and body fat significantly correlated with spirometric parameters. Right hand-grip strength, left hand-grip strength, and Sargent jump also significantly correlated with FVC and FEV1. [Conclusion] In order to improve the pulmonary function of children and adolescents, aerobic exercise and an exercise program to increase muscle strength and power is needed, and it should start in the late period of elementary school when muscle strength and power are rapidly increasing.

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Section: Discussionsupporting

confidence: 93%

Correlation between basic physical fitness and pulmonary function in Korean children and adolescents: a cross-sectional survey

et al. 2015

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“…Racial differences in lung function have been reported. The lung volume capacity of Korean children was found to be similar to that of Japanese and Chinese but lower than that of American children [7]. The FEV 1 and FVC in Caucasians were found to be larger than in Chinese and Indians.…”

Section: Discussionmentioning

confidence: 68%

“…Spirometric values are affected by individual factors such as height, age, sex, activity level, ethnicity and amount of muscles, environmental factors such as smoking, occupation, residence and air pollution, and technical factors such as spirometers, subjects, technicians and techniques [ 2 , 15 , 16 ]. In many countries, various studies evaluated the relationships between variables and spirometric values, and most of them said height was most related to spirometric values [ 3 , 4 , 5 , 6 , 7 , 9 , 10 , 11 , 12 , 13 , 14 ].…”

Section: Discussionmentioning

confidence: 99%

“…Age, sex and anthropometric factors, such as height and weight, affect reference values especially in childhood [ 2 ]. There have been several reports to obtain reference equations for Korean children since the early 1990s [ 3 , 4 , 5 , 6 , 7 ]. However, most of their subjects were recruited in the same region and the number of subjects was small.…”

Section: Introductionmentioning

confidence: 99%

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Normal Predicted Reference Values for Spirometry in Korean Children and Adolescents

Kim

Lim

2020

Children

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Pulmonary function tests are useful to evaluate airway obstructions and bronchial responsiveness. We aimed to determine the reference values applicable to Korean children and adolescents. In total, 5590 (2607 males, 2983 females) healthy children aged 4 to 17 years old were recruited from three regions in Korea. Simple and multiple regression analyses were applied using age, height, and weight as variables to predict the forced vital capacity (FVC), forced expiratory volume in one second (FEV1), maximum mid-expiratory flow (MMEF) and the peak expiratory flow rate (PEFR). There were significant correlations between the variables and parameters (P < 0.001). The coefficient of determination (R2) values of polynomial equations with two variables were lower than those with two variables but higher than those of monomial equations based on height. The prediction equations by height were obtained, and the R2 value of the FEV1 was the highest. The predicted spirometric values for males were higher than those for females except for the MMEF. The R2 values for the FEV1 and FVC were higher than previous studies except for the R2 value of the FVC for males in European data. This study provided updated regression equations of normal predicted values for spirometry applicable to Korean children and adolescents.

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“…Forced vital capacity (FVC), forced expiratory volume in one second (FEV1) and forced expiratory ow at 25-75% of FVC (FEF 25-75%) were measured in triplicate and the highest measurement was taken. The test was performed according to the American Thoracic Society standard test and the determination of decreased lung function was based on the study by Park et al (Normalized spirometric values in Korean children) [13].…”

Section: Pulmonary Function Test (Pft)mentioning

confidence: 99%

IL-1β and iNOS May Contribute to Asthmatic Comorbidities and Decreased Lung Function in Children with Perennial Allergic Rhinitis

Kim

Lee

et al. 2023

Preprint

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Background: Asthma and Allergic Rhinitis (AR) often coexist, with a significant number of AR patients eventually developing asthma. Early detection and treatment of AR can prevent disease progression and enhance the quality of life. Objectives and Methods: This study explores the roles of Interleukin-1β (IL-1β), a pro-inflammatory cytokine, and inducible Nitric Oxide Synthase (iNOS) in the comorbidity of AR and asthma, as well as their impact on lung function in Korean children with perennial AR. A cohort of 240 subjects (aged 6-10 years old) with AR and comorbid asthma were assessed for various biomarkers, including IL-1β, iNOS, and Epithelial-Mesenchymal Transition (EMT) markers. We examined the blood levels of eosinophils and Immunoglobulin E (IgE). IL-1β, CCL-24, E-cadherin, and vimentin were measured using Enzyme-Linked Immunosorbent Assay (ELISA), while epithelial iNOS was evaluated with the NOS kit. Results: Our observations revealed that elevated serum levels of IL-1β, iNOS, and vimentin emerged as significant risk factors for the development of AR and asthma comorbidity. Additionally, IL-1β, iNOS, and vimentin were identified as significant risk factors for decreased lung function in children with perennial AR. Moreover, IL-1β expression was found to correlate with the expression of E-cadherin, vimentin, and CCL-24. iNOS expression correlated with the expression of CCL-24 in children with AR. However, there was no observed correlation between IL-1β and iNOS. Conclusions: This study underscores the significance of IL-1β and iNOS in the progression of AR and asthma comorbidity, suggesting them as potential targets for early intervention and treatment.

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Predicted normal values of pulmonary function tests in normal Korean children

Cited by 11 publications

References 15 publications

Correlation between basic physical fitness and pulmonary function in Korean children and adolescents: a cross-sectional survey

Correlation between basic physical fitness and pulmonary function in Korean children and adolescents: a cross-sectional survey

Normal Predicted Reference Values for Spirometry in Korean Children and Adolescents

IL-1β and iNOS May Contribute to Asthmatic Comorbidities and Decreased Lung Function in Children with Perennial Allergic Rhinitis

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