Abstract:Background and purpose
To predict treatment-related cardiovascular disease (CVD) and second cancer 30-year absolute mortality risks (AMR30) for patients with mediastinal Hodgkin lymphoma in a large multicentre radiation oncology network in Ireland.
Material and methods
This study includes consecutive patients treated for mediastinal lymphoma using chemotherapy and involved site radiotherapy (RT) 2016–2019. Radiation doses to heart, left ventricle, cardiac … Show more
“…Houlihan et al [32 ▪ ] introduced a method for predicting treatment-related second cancer and absolute mortality risks (AMR 30 ) in patients with mediastinal Hodgkin lymphoma who underwent photon radiation therapy. The research group suggested that planning techniques using volumetric-modulated arc therapy, in combination with deep inspiration breath-hold are linked to reduced doses to the heart, lungs, and breasts.…”
Purpose of review
The significantly improved survivorship in Hodgkin lymphoma is fraught with challenges, including persistent symptoms, secondary health complications, and socio-professional obstacles. This review highlights the need for comprehensive survivorship care plans that include detection of relapse, assessment of long-term side effects, screening for secondary cancers, psychological support, and assistance with socio-professional integration.
Recent findings
Cardiovascular diseases, secondary malignancies and other associated risks remains an important problem related to the effective treatment of patients with Hodgkin lymphoma. Furthermore, fertility concerns and endocrine disorders remain prevalent issues posttreatment. An optimal evaluation of the risks before and after treatment is essential to reduce the impact of these side effects on quality of life. Addressing the socio-professional reintegration of survivors, the concept of the ‘Right to be forgotten’ emerges as a critical consideration. This principle seeks to eliminate discrimination against cancer survivors in accessing financial services and aims for legislative changes to ensure that past cancer diagnosis does not unfairly affect survivors’ futures. Implementation of this ‘Right to be forgotten’ in the legislature, is currently underway in European countries.
Summary
The focus of survivorship care has shifted towards the holistic management of these long-term outcomes. Quality of life for Hodgkin lymphoma survivors is affected by various treatment-related factors, with evidence suggesting that physical, psychological and socio-professional domains remain impacted years after treatment.
“…Houlihan et al [32 ▪ ] introduced a method for predicting treatment-related second cancer and absolute mortality risks (AMR 30 ) in patients with mediastinal Hodgkin lymphoma who underwent photon radiation therapy. The research group suggested that planning techniques using volumetric-modulated arc therapy, in combination with deep inspiration breath-hold are linked to reduced doses to the heart, lungs, and breasts.…”
Purpose of review
The significantly improved survivorship in Hodgkin lymphoma is fraught with challenges, including persistent symptoms, secondary health complications, and socio-professional obstacles. This review highlights the need for comprehensive survivorship care plans that include detection of relapse, assessment of long-term side effects, screening for secondary cancers, psychological support, and assistance with socio-professional integration.
Recent findings
Cardiovascular diseases, secondary malignancies and other associated risks remains an important problem related to the effective treatment of patients with Hodgkin lymphoma. Furthermore, fertility concerns and endocrine disorders remain prevalent issues posttreatment. An optimal evaluation of the risks before and after treatment is essential to reduce the impact of these side effects on quality of life. Addressing the socio-professional reintegration of survivors, the concept of the ‘Right to be forgotten’ emerges as a critical consideration. This principle seeks to eliminate discrimination against cancer survivors in accessing financial services and aims for legislative changes to ensure that past cancer diagnosis does not unfairly affect survivors’ futures. Implementation of this ‘Right to be forgotten’ in the legislature, is currently underway in European countries.
Summary
The focus of survivorship care has shifted towards the holistic management of these long-term outcomes. Quality of life for Hodgkin lymphoma survivors is affected by various treatment-related factors, with evidence suggesting that physical, psychological and socio-professional domains remain impacted years after treatment.
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